63296-55-9

Basic information

• Product Name: Propanoic acid, 2-[(phenylmethoxy)methoxy]-, ethyl ester, (S)-
• CAS NO: 63296-55-9
• Molecular Formula: C13H18O4
• Molecular Weight: 238.284
• Mol File: 63296-55-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-[(phenylmethoxy)methoxy]-, ethyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-[(phenylmethoxy)methoxy]-, ethyl ester, (S)-(63296-55-9)
• EPA Substance Registry System: Propanoic acid, 2-[(phenylmethoxy)methoxy]-, ethyl ester, (S)-(63296-55-9)

Safety Data

• Hazardous Substances Data: 63296-55-9(Hazardous Substances Data)

Upstream product

• 7699-00-5 (R)-Ethyl lactate 
• 3587-60-8 Benzyloxymethyl chloride 
• 687-47-8 (S)-Ethyl lactate 

Downstream Products

• 129602-81-9 (S)-(-)-4-benzyloxymethoxy-1-phenylpent-1-yn-3-one 
• 91191-94-5 (S)-(+)-2-<(benzyloxy)methoxy>propan-1-ol 
• 63296-56-0 (S)-(benzyloxymethoxy)propanal 
• 96823-45-9 (2R,5R,6R)-6-benzyloxymethoxy-5-ethyl-2-methoxyethoxymethoxyheptane-1,5-diol 
• 96823-35-7 (2S,6R)-2-benzyloxymethoxy-7-(4-methoxybenzyloxy)-6-methoxyethoxymethoxyheptan-3-one 
• 96823-37-9 (2R,5R,6S)-5-benzyloxy-6-benzyloxymethoxy-5-ethyl-2-methoxyethoxymethoxyheptan-1-ol 
• 96823-36-8 (2S,3R,6R)-2-benzyloxymethoxy-3-ethyl-7-(4-methoxybenzyloxy)-6-methoxyethoxymethoxyheptan-3-ol 
• 126393-85-9 (2S,6S)-2-benzyloxymethoxy-7-(4-methoxybenzyloxy)-6-methoxyethoxymethoxyhept-3-en-3-one 
• 96823-46-0 (2R,5R,6S)-5-Benzyloxy-6-benzyloxymethoxy-5-ethyl-2-(2-methoxy-ethoxymethoxy)-heptanal 
• 96823-47-1 (6R,9R,10S)-9-Benzyloxy-10-benzyloxymethoxy-9-ethyl-6-(2-methoxy-ethoxymethoxy)-undec-1-en-5-ol 
• 96823-39-1 (5S,6R,9R,10S)-9-benzyloxy-10-benzyloxymethoxy-9-ethyl-6-methoxyethoxymethoxy-5-methylundec-1-en-5-ol 
• 96823-38-0 (6R,9R,10S)-9-benzyloxy-10-benzyloxymethoxy-9-ethyl-6-methoxyethoxymethoxyundec-1-en-5-one 
• 126394-47-6 (2S,3R,6R)-3-benzyloxy-2-benzyloxymethoxy-3-ethyl-7-(4-methoxybenzyloxy)-6-methoxyethoxymethoxyheptane 
• 96823-34-6 Dimethyl [(3R)-3-benzyloxymethoxy-2-oxobutyl]phosphonate 

Relevant articles and documents

THE STEREOSPECIFIC SYNTHESIS OF (S)-2-2H3>METHYL-2-METHYLBUTANOL. CHARACTERISATION OF THE (R) AND (S) ENANTIOMERS OF THE RACEMIC 2H3>ALCOHOL BY 2H-NMR IN THE PRESENCE OF A CHIRAL SHIFT REAGENT.

The synthesis of the title compound is described.Assigment have been made in the 2H-NMR spectrum for the 2H3>methyl resonances of racemic 2-2H3>methyl-2-methylbutanol which were rendered anisochronous by the presence of tris(3-heptafluorobutyryl-d-camphorato)europium(III).

Acyclic stereoselection in the tertiary amine-catalysed addition of activated vinyl systems (Baylis-Hillman reaction) to protected chiral α-hydroxy and α-amino aldehydes

The non chelation-controlled aldol-type addition of the ambident vinyl α anions derived from acrylic esters and methyl vinyl ketone to a series of protected chiral α-hydroxy and α-amino aldehydes has been investigated in order to assess some of the factors which contribute to the control of the diastereofacial selectivity.Whlist the α-methylene-β,γ-disubstituted carbonyl products showed a general preference for selectivity, some examples of syn predominance were made possible via a 'substituent tuning'approach.The observed diastereomer ratios have been interpreted in terms of the Felkin model and the Anh-Eisenstein proposals for 1,2-asymmetric induction.Simple steric effects appear to be as important as ?-orbital energies in the designation of the large 'anti group' for the application of these transition-state interpretations.Attempts to improve the overall induction via double diastereoselection approach, which combines the 1,5-induction of chiral acrylates with the 1,2-induction already present, were largely inconclusive.Methods for the routine NMR assignment of the relevant stereo-substructures have been assessed and the use of novel complementary technique is described.

Enantiotopic group differentiation and kinetic resolution: Asymmetric reduction of meso-1,3-dihalides

Asymmetric reduction of 1,3-dihalides derived from glycerol occurs with moderate levels of enantiotopic group differentiation. A concomitant kinetic resolution increases the enantiometric purity of the initial product.