63320-66-1Relevant articles and documents
Oxidative aryl-aryl, aryl-benzyl coupling of lignans-reactions of phyllanthin and haloderivatives with TTFA, DDQ, Li/THF)))): Synthesis of dibenzocyclooctadiene system and phyltetralin
Satyanarayana,Venkateswarlu,Viswanatham
, p. 8277 - 8284 (2007/10/02)
Treatment of phyllanthin (1) with TTFA in TFA gives dibenzocyclooctadiene (2) and phyltetralin (3). Treatment of (1) with DDQ in TFA also affords (2) while with DDQ in acetic acid gives 1-phenylnaphthalenic lignan (4). Synthesis of halophyllanthins (5,6,7) and its Ullmann reaction in ultrasonic condition affords reductive dehalogenated product (1) instead of (2). Treatment of (1) with POCl3 in TCA gives (+) 3,4-diveratryltetrahydrofuran (8) and its conversion to (9) also reported. Treatment of (5) with TTFA/TFA gives (9).
The Preparation of Lignans via Intermolecular Cycloadditions with Quinodimethanes
Mann, John,Piper, Susan E.
, p. 430 - 432 (2007/10/02)
Certain lignans can be prepared using, as the key step, a thermal reaction between 1-(aryl)-1,3-dihydro-5,6-dialkoxy-benzothiophen 2,2-dioxides and dienophiles.
STRUCTURE AND SYNTHESYS OF HYPOPHYLLANTHIN, NIRTETRALIN, PHYLTETRALIN AND LINTETRALIN
Ganeshpure, Pralhad A.,Schneiders, Gail E,Stevenson, Robert
, p. 393 - 396 (2007/10/02)
Structures propounded for the four aryltetralin lignan constituents isolated from Phyllanthus niruri Linn. are confirmed by syntheses of their (+/-)-forms.