63328-49-4

Basic information

• Product Name: (R)-2-amino-6-tert-butoxycarbonylaminohexanoic acid methyl ester
• Synonyms: (R)-2-amino-6-tert-butoxycarbonylaminohexanoic acid methyl ester
• CAS NO: 63328-49-4
• Molecular Weight: 260.334
• Mol File: 63328-49-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (R)-2-amino-6-tert-butoxycarbonylaminohexanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-amino-6-tert-butoxycarbonylaminohexanoic acid methyl ester(63328-49-4)
• EPA Substance Registry System: (R)-2-amino-6-tert-butoxycarbonylaminohexanoic acid methyl ester(63328-49-4)

Safety Data

• Hazardous Substances Data: 63328-49-4(Hazardous Substances Data)

Upstream product

• 84559-78-4 methyl (2R)-2-[[(benzyloxy)carbonyl]amino]-6-[[(tert-butoxy)carbonyl]amino]hexanoate 
• 92122-45-7 Fmoc-D-Lys(BOC)-OH 
• 172846-57-0 C₂₇H₃₄N₂O₆ 
• 66845-42-9 N^α-(benzyloxycarbonyl)-N^ε-(tert-butoxycarbonyl)-D-lysine 

Downstream Products

• 1043890-21-6 (R)-2-(4-fluoro-3,5-dimethylphenylamino)-6-(3-nitrobenzenesulfonylamino)hexanoic acid hydroxy amide 
• 1043890-17-0 (R)-2-(4-fluoro-3,5-dimethylphenylamino)-6-(4-fluoro-3-methylbenzylamino)-N-hydroxyhexanamide 
• 1043890-90-9 (R)-2-(4-fluoro-3,5-dimethylphenylamino)-6-(3-nitrobenzenesulfonylamino)hexanoic acid methyl ester 
• 1043890-91-0 (R)-methyl 2-(4-fluoro-3,5-dimethylphenylamino)-6-(4-fluoro-3-methylbenzylamino)hexanoate 
• 1043890-89-6 (R)-6-amino-2-(4-fluoro-3,5-dimethylphenylamino)hexanoic acid methyl ester 

Relevant articles and documents

Synthesis and antibacterial activity of C2-symmetric binaphthyl scaffolded amino acid derivatives

The synthesis of eleven novel antibacterial agents is reported. The structures are based on a C2-symmetric binaphthyl scaffold which holds two identical chains consisting of a short linker, a basic amino acid and a small hydrophobic side chain.

FACTOR XIIa INHIBITORS

The present invention provides a compound of Formula I and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIIa inhibitors.