63333-26-6Relevant articles and documents
Alkylarylamine compound and preparation method thereof
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Paragraph 0044-0052, (2021/10/27)
The invention discloses an alkylarylamine compound and preparation method thereof. The preparation method mainly comprises the following steps: dissolving an alkyl compound, a nitro compound, an acid and a photocatalyst in a solvent; carrying out an illumination reaction at room temperature; after the reaction is finished, carrying out alkali neutralization, ethyl acetate extraction and reduced-pressure distillation to remove the solvent; and carrying out column chromatography separation to obtain the alkylarylamine compound. Compared with an alkylarylamine compound which has been widely researched and reported, the alkylarylamine compound provided by the invention has the advantages of simple operation, simple steps, high atom utilization rate, stable chemical properties, low cost, easy purification and the like; and since an alkyl group is directly activated, the method can realize conversion from low-added-value chemicals to high-added-value chemicals, and provides convenience for organic synthesis chemistry and drug synthesis.
