63335-24-0

Basic information

• Product Name: Malabaricone B
• Synonyms: Malabaricone B;1-(2,6-Dihydroxyphenyl)-9-(4-hydroxyphenyl)-1-nonanone
• CAS NO: 63335-24-0
• Molecular Formula: C₂₁H₂₆O₄
• Molecular Weight: 342.43
• Mol File: 63335-24-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 100-102 °C
• Boiling Point: 536.4°C at 760 mmHg
• Flash Point: 292.3°C
• Appearance: /
• Density: 1.17g/cm³
• Vapor Pressure: 4.04E-12mmHg at 25°C
• Refractive Index: 1.59
• PKA: 7.48±0.35(Predicted)
• CAS DataBase Reference: Malabaricone B(CAS DataBase Reference)
• NIST Chemistry Reference: Malabaricone B(63335-24-0)
• EPA Substance Registry System: Malabaricone B(63335-24-0)

Safety Data

• Hazardous Substances Data: 63335-24-0(Hazardous Substances Data)

Usage

General Description

Malabaricone B is a natural compound found in the fruit of Myristica malabarica, a plant native to the Western Ghats in India. It has been identified as a potential therapeutic agent due to its anti-inflammatory, antioxidant, and antimicrobial properties. Malabaricone B has been shown to inhibit the production of pro-inflammatory molecules, suppress the growth of harmful bacteria, and scavenge harmful free radicals. It also has potential use in the treatment of various diseases, including cancer and inflammatory conditions. Its unique chemical structure and diverse biological activities make Malabaricone B a promising candidate for the development of new drugs and therapies.

InChI:InChI=1/C21H26O4/c22-17-14-12-16(13-15-17)8-5-3-1-2-4-6-9-18(23)21-19(24)10-7-11-20(21)25/h7,10-15,22,24-25H,1-6,8-9H2

Upstream product

• 133839-79-9 1-(2,6-Dihydroxyphenyl)-9-(4-methoxyphenyl)nonan-1-one 
• 699-83-2 2,6-dihydroxylacetophenone 
• 54247-27-7 1-bromo-6-benzyloxyhexane 
• 4047-24-9 1-[2-(benzyloxy)-6-hydroxyphenyl]ethanone 
• 71126-73-3 6-benzyloxyhexan-1-ol 
• 133839-61-9 7-(4-methoxyphenyl)-heptan-1-ol 
• 133839-63-1 7-(4-methoxyphenyl)-heptan-1-al 
• 133839-58-4 (Z)-1-Benzyloxy-7-(4-methoxyphenyl)hept-6-ene 
• 133839-75-5 (E)-1-(2-Benzyloxy-6-hydroxyphenyl)-9-(4-methoxyphenyl)-2-nonen-1-one 
• 133839-68-6 1-(2-Benzyloxy-6-hydroxyphenyl)-3-hydroxy-9-(4-methoxyphenyl)nonan-1-one 
• 125732-13-0 ethyl 3-(2,6-dimethoxyphenyl)-3-oxopropanoate 
• 2040-04-2 2,6-dimethoxyacetophenone 

Relevant articles and documents

Cytotoxic acylphenols from Myristica maingayi

From the cytotoxic AcOEt extract of the fruits of Myristica maingayi, a Myristicaceae, five new acylphenols (promalabaricones B and C, maingayic acids B and C, and maingayone) were isolated, together with the known malabaricones A-C. The structures were determined from spectral analysis, including mass spectrometry and 2D NMR. The cytotoxicity of the new compounds and that of malabaricones was assessed against KB cells. A biosynthetic pathway for malabaricones, via the corresponding promalabaricones as precursors, is suggested. (C) 2000 Elsevier Science Ltd.

Synthesis of malabaricones, diarylnonanoids occurring in myristicaceous plants

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