63351-45-1

Basic information

• Product Name: Benzamide, N-(3-chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)-
• CAS NO: 63351-45-1
• Molecular Formula: C17H10ClNO3
• Molecular Weight: 311.724
• Mol File: 63351-45-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzamide, N-(3-chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-(3-chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)-(63351-45-1)
• EPA Substance Registry System: Benzamide, N-(3-chloro-1,4-dihydro-1,4-dioxo-2-naphthalenyl)-(63351-45-1)

Safety Data

• Hazardous Substances Data: 63351-45-1(Hazardous Substances Data)

Upstream product

• 2797-51-5 quinoclamine 
• 98-88-4 benzoyl chloride 
• 117-80-6 2,3-Dichloro-1,4-naphthoquinone 

Downstream Products

• 63388-44-3 2-phenyl-4,9-dioxo-4,9-dihydro-naphtho[2,3-d]oxazole 
• 1610042-71-1 N-(3-(furan-3-yl)-1,4-dioxo-1,4-dihydronaphthalen-2-yl)benzamide 
• 1610042-70-0 N-(3-(3-formylphenyl)-1,4-dioxo-1,4-dihydronaphthalen-2-yl)benzamide 
• 1610042-66-4 N-(3-(3,5-dimethylphenylamino)-1,4-dioxo-1,4-dihydronaphthalen-2-yl)benzamide 
• 175090-50-3 N-(3-Ethylamino-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)-benzamide 

Relevant articles and documents

INHIBITORS OF THE MITF MOLECULAR PATHWAY

Provided herein are compounds of the formula (IV) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful as MITF inhibitors, MITF pathway inhibitors and for the treatment of cancer.

Synthesis and evaluation of Hsp90 inhibitors that contain the 1,4-naphthoquinone scaffold

High-throughput screening of a library of diverse molecules has identified the 1,4-naphthoquinone scaffold as a new class of Hsp90 inhibitors. The synthesis and evaluation of a rationally-designed series of analogues containing the naphthoquinone core sca

Synthesis and antiplatelet, antiinflammatory, and antiallergic activities of 2-substituted 3-chloro-1,4-naphthoquinone derivatives

A series of 2-substituted 3-chloro-1,4-naphthoquinones was synthesized, and the antiplatelet, antiinflammatory, and antiallergic activities of these compounds were evaluated. The structure-activity relationships in this series were also examined. Most of the 2-alkyl/arylcarboxamido derivatives of 3-chloro-1,4-naphthoquinone showed potent activities with similar trends in each of the activities evaluated.