6336-79-4Relevant articles and documents
One-pot synthesis of (R)-2-acetoxy-1-indanone from 1,2-indanedione combining metal catalyzed hydrogenation and chemoenzymatic dynamic kinetic resolution
Langvik, Otto,Sandberg, Thomas,W?rna, Johan,Murzin, Dmitry Yu.,Leino, Reko
, p. 150 - 160 (2015)
Combination of the regioselective hydrogenation of the prochiral diketone 1,2-indanedione with chemoenzymatic dynamic kinetic resolution of the resulting rac-2-hydroxy-1-indanone was investigated. A new simple to operate, one-pot reaction sequence provides the valuable building block (R)-2-acetoxy-1-indanone in moderate enantiopurity (86-92% ee) and a competitive isolated yield (39%) compared with a traditional isolated batch reaction approach.
Synthesis of catechols from phenols via Pd-catalyzed silanol-directed C-H oxygenation
Huang, Chunhui,Ghavtadze, Nugzar,Chattopadhyay, Buddhadeb,Gevorgyan, Vladimir
supporting information; experimental part, p. 17630 - 17633 (2011/12/16)
A silanol-directed, Pd-catalyzed C-H oxygenation of phenols into catechols is presented. This method is highly site selective and general, as it allows for oxygenation of not only electron-neutral but also electron-poor phenols. This method operates via a silanol-directed acetoxylation, followed by a subsequent acid-catalyzed cyclization reaction into a cyclic silicon-protected catechol. A routine desilylation of the silacyle with TBAF uncovers the catechol product.
Molecular Rearrangements and Fragmentations during the Aromatization of Diels-Alder Adducts Derived from 1-Benzylisobenzofuran
Smith, James G.,Chu, Noreen G.
, p. 4083 - 4085 (2007/10/02)
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