63364-56-7Relevant articles and documents
ASYMMETRIC SYNTHESIS OF CIS AND TRANS 2-METHYL AND 2-ETHYL 1-AMINO CYCLOPROPANECARBOXYLIC ACIDS
Alami, Adiba,Calmes, Monique,Daunis, Jacques,Escale, Francoise,Jacquier, Robert,et al.
, p. 175 - 178 (1991)
A new four step asymmetric synthesis of 2-methyl and 2-ethyl 1-amino cyclopropane carboxylic acids resulted from the cycloaddition of diazomethane to the corresponding chirally derivatized dehydro-aminoacid.
Titanium-mediated diastereoselective formation of (E)- or (Z)-2-substituted 1-vinylcyclopropanols: Scope and limitation, applications
Racouchot, Sandrine,Sylvestre, Isabelle,Ollivier, Jean,Kozyrkov, Yuri Yu.,Pukin, Alexei,Kulinkovich, Oleg G.,Salauen, Jacques
, p. 2160 - 2176 (2007/10/03)
Titanium-mediated cyclopropanation of α,β-unsaturated esters failed to provide 1-vinylcyclopropanol derivatives in useful yields, but (E)-2-substituted-1-vinylcyclopropanols were formed diastereoselectively from O-protected β-oxo- and β-halo esters, with the allylic double bond being created subsequently (Knoevenagel condensation or dehydrohalogenation). Titanium-mediated cyclopropanation of homoallyl alk-2-enoates, on the other hand, directly provided the corresponding Z diastereomers. Palladium(0)-catalysed azidation of their sulfonic esters (tosylate, mesylate), azide reduction, and subsequent double bond cleavage afforded (E)- or (Z)-2-alkyl-2,3-methanoamino acids, although improvements are required to perform the total asymmetric syntheses of molecules with three membered-rings by these methods. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.
Utilization of [2 + 1] cycloaddition reactions of 1-seleno-2- silylethenes: A novel synthesis of 2-substituted 1-aminocyclopropane-1- carboxylic acids
Yamazaki, Shoko,Inoue, Takashi,Hamada, Taro,Takada, Takashi,Yamamoto, Kagetoshi
, p. 282 - 286 (2007/10/03)
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