6338-84-7

Basic information

• Product Name: 1,3,7-trimethyl-8-(2-phenylethyl)-3,7-dihydro-1H-purine-2,6-dione
• CAS NO: 6338-84-7
• Molecular Formula: C₁₆H₁₈N₄O₂
• Molecular Weight: 298.3397
• Mol File: 6338-84-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 518.8°C at 760 mmHg
• Flash Point: 267.6°C
• Density: 1.27g/cm³
• Vapor Pressure: 7.23E-11mmHg at 25°C
• Refractive Index: 1.644
• CAS DataBase Reference: 1,3,7-trimethyl-8-(2-phenylethyl)-3,7-dihydro-1H-purine-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,7-trimethyl-8-(2-phenylethyl)-3,7-dihydro-1H-purine-2,6-dione(6338-84-7)
• EPA Substance Registry System: 1,3,7-trimethyl-8-(2-phenylethyl)-3,7-dihydro-1H-purine-2,6-dione(6338-84-7)

Safety Data

• Hazardous Substances Data: 6338-84-7(Hazardous Substances Data)

Usage

Chemical structure

A xanthine derivative produced from the metabolism of caffeine in the human body.

Stimulating effect

Similar to caffeine, but less potent in its effects on the central nervous system.

Diuretic properties

Acts as a mild diuretic, helping to increase urine production and excretion.

Bronchodilator potential

Has been found to have some potential as a bronchodilator, which could help in treating respiratory conditions.

Liver disease treatment

Has been studied for its potential as a treatment for liver disease, indicating possible therapeutic applications.

Enhanced lipolysis

Has the ability to enhance lipolysis, which is the breakdown of fats in the body.

Reduced adipose tissue accumulation

May help in reducing the accumulation of adipose (fat) tissue.

Upstream product

• 126235-09-4 NSC 14319 
• 74-88-4 methyl iodide 
• 5440-00-6 4,5-Diamino-1,3-dimethyluracil 
• 501-52-0 3-Phenylpropionic acid 
• 58-08-2 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione 
• 34420-17-2 (2-phenylethyl)boronic acid 

Relevant articles and documents

Photoredox-mediated Minisci C-H alkylation of N-heteroarenes using boronic acids and hypervalent iodine

A photoredox-mediated Minisci C-H alkylation reaction of N-heteroarenes with alkyl boronic acids is reported. A broad range of primary and secondary alkyl groups can be efficiently incorporated into various N-heteroarenes using [Ru(bpy)3]Cl2 as photocatalyst and acetoxybenziodoxole as oxidant under mild conditions. The reaction exhibits excellent substrate scope and functional group tolerance, and offers a broadly applicable method for late-stage functionalization of complex substrates. Mechanistic experiments and computational studies suggest that an intramolecularly stabilized ortho-iodobenzoyloxy radical intermediate might play a key role in this reaction system.

Inhibition of monoamine oxidase by selected phenylalkylcaffeine analogues

Objectives Caffeine represents a useful scaffold for the design of monoamine oxidase (MAO) type B inhibitors. Specifically, substitution on the C8 position yields structures which are high-potency MAO-B inhibitors. To explore the structure-activity relati