63403-26-9Relevant articles and documents
Quantitative structure activity relationship studies in pyrethroid esters derived from substituted 3-methyl-2-phenoxybutanoic acids against Culex quinquefasciatus
Mathew, Nisha,Subramanian,Kalyanasundaram
, p. 40 - 44 (2007/10/03)
QSAR studies in relation to three physicochemical substituent parameters, lipophilicity, electronic and steric factors have been carried out with pyrethroid esters derived from substituted 3-methyl-2-phenoxybutanoic acids against Culex quinquefasciatus applying multiple regression analysis by grouping the esters into three based on their alcohol moiety. In the case of 3-phenoxybenzyl and α-cyano-3-phenoxybenzyl esters the larvicidal activity is mainly influenced by the lipophilic and electronic nature of the substituent at 4-position of the phenyl ring of the acid moiety. For adulticidal activity the lipophilicity of the substituent at 4-position followed by that of the substituents at 2-and 3-positions along with the steric effect are the important factors for 3-phenoxybenzyl and α-cyano-3-phenoxybenzyl esters. The larvicidal and adulticidal activities of 3,4-methylenedioxybenzyl esters are influenced by electronic factor followed by steric effect of the substituent.
