63413-74-1

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-[(4-ethenylphenyl)methyl]-
• CAS NO: 63413-74-1
• Molecular Formula: C17H13NO2
• Molecular Weight: 263.296
• Mol File: 63413-74-1.mol
• Article Data: 29

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-[(4-ethenylphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-[(4-ethenylphenyl)methyl]-(63413-74-1)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-[(4-ethenylphenyl)methyl]-(63413-74-1)

Safety Data

• Hazardous Substances Data: 63413-74-1(Hazardous Substances Data)

Usage

Structure

1H-Isoindole-1,3(2H)-dione, 2-[(4-ethenylphenyl)methyl]-

Derivative

Phthalimide derivative

Contains

A vinyl group attached to a phenyl ring

Usage

Organic synthesis as a starting material for the preparation of various substances, including pharmaceuticals and agrochemicals

Potential

Demonstrated potential biological activity and is being studied for its pharmacological properties

Also used as

A reagent in chemical reactions, such as the synthesis of various organic compounds and polymers.

Upstream product

• 73291-09-5 4-chloromethylbenzaldehyde 
• 51359-79-6 4-((1,3-dioxoisoindolin-2-yl)methyl)benzaldehyde 
• 19493-09-5 Methylenetriphenylphosphorane 
• 136918-14-4 phthalimide 
• 1592-20-7 4-Vinylbenzyl chloride 
• 1074-82-4 potassium phtalimide 

Downstream Products

• 1631035-54-5 2-(4-(1-fluoroethyl)benzyl)isoindoline-1,3-dione 

Relevant articles and documents

Transition metal-free formal hydro/deuteromethylthiolation of unactivated alkenes

Methylthioether is involved in the methylthiotransfer process in organisms, and therefore its functionality is of paramount importance to living organisms. Several methods for the installation of the methylthio group in small molecules have been reported previously; however, procedures starting from unactivated alkenes are rare. Herein, we report a formal hydro/deuteromethylthiolation of alkenes by using dimethyl(methylthio)sulfonium trifluoromethanesulfonate as the stimulator and sodium borohydride/deuteride as the hydrogen/deuterium source. The process represents a mild, transition metal-free and methanethiol-free route towards the synthesis of methylthioethers from unactivated alkenes. This journal is

Overcoming Selectivity Issues in Reversible Catalysis: A Transfer Hydrocyanation Exhibiting High Kinetic Control

Reversible catalytic reactions operate under thermodynamic control, and thus, establishing a selective catalytic system poses a considerable challenge. Herein, we report a reversible transfer hydrocyanation protocol that exhibits high selectivity for the thermodynamically less favorable branched isomer. Selectivity is achieved by exploiting the lower barrier for C-CN oxidative addition and reductive elimination at benzylic positions in the absence of a cocatalytic Lewis acid. Through the design of a novel type of HCN donor, a practical, branched-selective, HCN-free transfer hydrocyanation was realized. The synthetically useful resolution of a mixture of branched and linear nitrile isomers was also demonstrated to underline the value of reversible and selective transfer reactions. In a broader context, this work demonstrates that high kinetic selectivity can be achieved in reversible transfer reactions, thus opening new horizons for their synthetic applications.

Heteroatom Donor-Decorated Polymer-Immobilized Ionic Liquid Stabilized Palladium Nanoparticles: Efficient Catalysts for Room-Temperature Suzuki-Miyaura Cross-Coupling in Aqueous Media

Palladium nanoparticles stabilized by heteroatom donor-modified polystyrene-based polymer immobilized ionic liquids (PdNP@HAD-PIILP; HAD-PPh2, OMe, NH2, CN, pyrrolidone) are highly efficient catalysts for the Suzuki-Miyaura cross-cou