63452-53-9

Basic information

• Product Name: AcetaMide, N-[(2-Methoxyphenyl)Methyl]-
• Synonyms: AcetaMide, N-[(2-Methoxyphenyl)Methyl]-
• CAS NO: 63452-53-9
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.21572
• Mol File: 63452-53-9.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: AcetaMide, N-[(2-Methoxyphenyl)Methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: AcetaMide, N-[(2-Methoxyphenyl)Methyl]-(63452-53-9)
• EPA Substance Registry System: AcetaMide, N-[(2-Methoxyphenyl)Methyl]-(63452-53-9)

Safety Data

• Hazardous Substances Data: 63452-53-9(Hazardous Substances Data)

Upstream product

• 6609-56-9 2-methoxy-benzonitrile 
• 6850-57-3 2-methoxybenzylamine 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 141-78-6 ethyl acetate 
• 60-35-5 acetamide 
• 135-02-4 ortho-anisaldehyde 
• 64-19-7 acetic acid 
• 2033-24-1 cycl-isopropylidene malonate 

Downstream Products

• 6850-57-3 2-methoxybenzylamine 
• 111088-28-9 Bis-[3-(acetylamino-methyl)-4-methoxy-phenyl]-iodonium; iodide 
• 111088-34-7 (S)-2-Acetylamino-3-{4-[3-(acetylamino-methyl)-4-methoxy-phenoxy]-3,5-diiodo-phenyl}-propionic acid ethyl ester 
• 111087-96-8 (S)-2-Amino-3-[4-(3-aminomethyl-4-hydroxy-phenoxy)-3,5-diiodo-phenyl]-propionic acid; hydrobromide 
• 62924-83-8 N-ethyl-N-[(2methoxyphenyl)methyl]amine 
• 1388628-63-4 3-(N-acetylaminomethyl)-3',4,4',5'-tetramethyloxy-(Z)-stilbene 
• 80311-94-0 N-(2-hydroxybenzyl)acetamide 
• 1448992-65-1 {3-[2-(acetylamino-methyl)-phenoxy]-propyl}-carbamic acid tert-butyl ester 
• 1448992-66-2 tert-butyl-3-(2-(aminomethyl)phenoxy)propylcarbamate 
• 1448992-68-4 [3-(2-isocyanatomethyl-phenoxy)-propyl]-carbamic acid tert-butyl ester 
• 1448992-67-3 [ (2-{3-[2-(3-tert-butoxycarbonylamino-propoxy)-benzyl]-ureido}thiazole-4-carbonyl)-amino]-acetic acid methyl ester 
• 1448992-69-5 [(2-{3-[2-(3-tert-butoxycarbonylamino-propoxy)-benzyl ]-ureido}-thiazole-4-carbonyl)-amino ]-acetic acid 
• 1448992-70-8 methyl-3-(2-(2-(3-(2-(3-(tert-butoxycarbonylamino)propoxy) benzyl)ureido )thiazole-4-carboxamido )acetamido )-3-phenylpropanoate 
• 1448992-73-1 (R)-ethyl-3-(2-(2-(3-(2-(3-(tert-butoxycarbonylamino)propoxy)benzyl)ureido)thiazole-4-carboxamido)acetamido)-3-(pyridin-3-yl)propanoate 

Relevant articles and documents

Reductive Amidation without an External Hydrogen Source Using Rhodium on Carbon Matrix as a Catalyst

An efficient method for preparation of secondary amides from primary amides and aldehydes using rhodium on carbon matrix as catalyst was developed. The method does not require any external hydrogen source and carbon monoxide is used as a reducing agent. The most active rhodium catalysts were characterized by BET, TEM and XPS techniques. Unexpectedly, it was found that heterogeneous rhodium on carbon matrix works as precatalyst for homogenous active species due to leaching of rhodium to the solution. Various secondary amides were synthesized and checked for antifungal activity. 4-Methoxy-N-(4-methoxybenzyl)benzamide demonstrated promising activity against Rhizoctonia Solani.

Iridium-Catalyzed Benzylamine C-H Alkenylation Enabled by Pentafluorobenzoyl as the Directing Group

The first iridium-catalyzed oxidative alkeynylation of benzylamines with acrylates enabled by a new directing group pentafluorobenzoyl has been developed. The reaction proceeded efficiently in the presence of silver acetate as oxidant and chlorobenzene as

Dichotomy of Atom-Economical Hydrogen-Free Reductive Amidation vs Exhaustive Reductive Amination

Rh-catalyzed one-step reductive amidation of aldehydes has been developed. The protocol does not require an external hydrogen source and employs carbon monoxide as a deoxygenative agent. The direction of the reaction can be altered simply by changing the solvent: reaction in THF leads to amides, whereas methanol favors formation of tertiary amines.