634616-03-8Relevant articles and documents
A Substructure Approach toward Polymeric Receptors Targeting Dihydrofolate Reductase Inhibitors. 2. Molecularly Imprinted Polymers against Z-L-Glutamic Acid Showing Affinity for Larger Molecules
Hall, Andrew J.,Achilli, Laura,Manesiotis, Panagiotis,Quaglia, Milena,De Lorenzi, Ersilia,Sellergren, Boerje
, p. 9132 - 9135 (2003)
The preparation of a molecularly imprinted polymer against N-Z-L-glutamic acid using a novel bis-urea functional monomer is described. The polymer exhibits affinity for the template over N-Z-protected aspartic acid and glycine and, further, is capable of binding larger molecules, e.g., the anti-cancer drug methotrexate, containing the glutamate substructure.
