63476-54-0

Basic information

• Product Name: 2-(4-formylphenyl)propionic acid methyl ester
• Synonyms: 2-(4-formylphenyl)propionic acid methyl ester
• CAS NO: 63476-54-0
• Molecular Weight: 192.214
• Mol File: 63476-54-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(4-formylphenyl)propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-formylphenyl)propionic acid methyl ester(63476-54-0)
• EPA Substance Registry System: 2-(4-formylphenyl)propionic acid methyl ester(63476-54-0)

Safety Data

• Hazardous Substances Data: 63476-54-0(Hazardous Substances Data)

Usage

Structure

An ester derivative of 2-(4-formylphenyl)propionic acid

Common uses

Intermediate in the synthesis of pharmaceutical compounds and organic materials, development of anti-inflammatory drugs, production of fragrances and flavors

Physical properties

Colorless to pale yellow liquid, fruity odor

Importance

Versatile reactivity and functional group compatibility in organic synthesis

Upstream product

• 79443-97-3 methyl 2-(4-methylphenyl)propanoate 
• 554-12-1 propanoic acid methyl ester 
• 100-52-7 benzaldehyde 
• 99807-54-2 2-(4-bromomethylphenyl)propionic acid methyl ester 
• 111128-12-2 2-[4-(bromomethyl)phenyl]propanoic acid 
• 938-94-3 (R,S)-2-(4'-methylphenyl) propionic acid 
• 2362-36-9 1-(1-chloroethyl)-4-methylbenzene 

Downstream Products

• 81762-92-7 loxoprofen methyl ester 
• 80382-23-6 sodium 2-<4-<(2-oxocyclopentyl)methyl>phenyl>propionate 
• 63476-38-0 2-[4-(3-Hydroxy-5-methyl-cyclohexyl)-phenyl]-propionic acid 
• 63476-37-9 2-[4-(3-Methyl-5-oxo-cyclohex-3-enyl)-phenyl]-propionic acid 

Relevant articles and documents

Metal- And additive-free C-H oxygenation of alkylarenes by visible-light photoredox catalysis

A metal- and additive-free methodology for the highly selective, photocatalyzed C-H oxygenation of alkylarenes under air to the corresponding carbonyls is presented. The process is catalyzed by an imide-acridinium that forms an extremely strong photooxidant upon visible light irradiation, which is able to activate inert alkylarenes such as toluene. Hence, this is an easy to perform, sustainable and environmentally friendly oxidation that provides valuable carbonyls from abundant, readily available compounds.

Method for preparing loxoprofen sodium

The invention relates to the technical field of organic synthesis, in particular to a method for preparing loxoprofen sodium. The invention provides a compound with the structure shown in formula 5 and a preparation method and application of the compound, (the formula is defined in the description). The loxoprofen sodium obtained according to the scheme is high in purity, high in industrialized operation, and good in application prospect.