63521-37-9

Basic information

• Product Name: 3-methylpentane-2,3-diol
• Synonyms: 3-methylpentane-2,3-diol;3-Methyl-2,3-pentanediol
• CAS NO: 63521-37-9
• Molecular Formula: C₆H₁₄O₂
• Molecular Weight: 118.17416
• EINECS: 264-294-4
• Mol File: 63521-37-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 26.38°C (estimate)
• Boiling Point: 221.7°C (rough estimate)
• Flash Point: 77°C
• Appearance: /
• Density: 0.9843 (rough estimate)
• Vapor Pressure: 0.204mmHg at 25°C
• Refractive Index: 1.4440
• PKA: 15.04±0.29(Predicted)
• CAS DataBase Reference: 3-methylpentane-2,3-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methylpentane-2,3-diol(63521-37-9)
• EPA Substance Registry System: 3-methylpentane-2,3-diol(63521-37-9)

Safety Data

• Hazardous Substances Data: 63521-37-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H14O2/c1-4-6(3,8)5(2)7/h5,7-8H,4H2,1-3H3

Upstream product

• 109916-61-2 3-hydroxy-3-methyl-pentan-2-one 
• 922-62-3 3-Methyl-cis-2-penten 
• 96-14-0 3-methylpentane 
• 64-17-5 ethanol 

Relevant articles and documents

A Colorimetric Method for Quantifying Cis and Trans Alkenes Using an Indicator Displacement Assay

A colorimetric indicator displacement assay (IDA) amenable to high-throughput experimentation was developed to determine the percentage of cis and trans alkenes. Using 96-well plates two steps are performed: a reaction plate for dihydroxylation of the alkenes followed by an IDA screening plate consisting of an indicator and a boronic acid. The dihydroxylation generates either erythro or threo vicinal diols from cis or trans alkenes, depending upon their syn- or anti-addition mechanisms. Threo diols preferentially associate with the boronic acid due to the creation of more stable boronate esters, thus displacing the indicator to a greater extent. The generality of the protocol was demonstrated using seven sets of cis and trans alkenes. Blind mixtures of cis and trans alkenes were made, resulting in an average error of ±2 % in the percentage of cis or trans alkenes, and implementing E2 and Wittig reactions gave errors of ±3 %. Furthermore, we developed variants of the IDA for which the color may be tuned to optimize the response for the human eye.

METAL-CATALYZED ORGANIC PHOTOREACTIONS. TITANIUM(IV) CHLORIDE-CATALYZED PHOTOREACTIONS OF ALCOHOLS AND FORMIC ESTERS

The UV-irradiation of some alcohols in the presence of titanium(IV) chloride gave products with a C-C bond formation between alcohol molecules.The titanium(IV) chloride-catalyzed photoreaction of formic esters in alcohols induced the formylation of alcohol at the α-position.