635713-71-2

Basic information

• Product Name: 1-N-BOC-5-FORMYL-INDAZOLE
• Synonyms: 1-N-BOC-5-FORMYL-INDAZOLE;1-(tert-Butoxycarbonyl)-1H-indazole-5-carboxaldehyde, 5-Formyl-1H-indazole, N1-BOC protected;1H-Indazole-5-carboxaldehyde, N1-BOC protected;tert-Butyl 5-formyl-1H-indazole-1-carboxylate;1-Boc-indazole-5-carboxaldehyde;1H-INDAZOLE-1-CARBOXYLIC ACID,5-FORMYL-,1,1-DIMETHYLETHYL ESTER
• CAS NO: 635713-71-2
• Molecular Formula: C₁₃H₁₄N₂O₃
• Molecular Weight: 246.26
• Mol File: 635713-71-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 390.3°C at 760 mmHg
• Flash Point: 189.8°C
• Appearance: /
• Density: 1.2g/cm³
• Vapor Pressure: 2.68E-06mmHg at 25°C
• Refractive Index: 1.574
• CAS DataBase Reference: 1-N-BOC-5-FORMYL-INDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-N-BOC-5-FORMYL-INDAZOLE(635713-71-2)
• EPA Substance Registry System: 1-N-BOC-5-FORMYL-INDAZOLE(635713-71-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 635713-71-2(Hazardous Substances Data)

Usage

Chemical class

Indazoles, which are heterocyclic aromatic compounds.

Substituents

5-formyl group at the 1-position of the indazole ring.

Protecting group

BOC (tert-butoxycarbonyl) group at the N-1 amino group.

Application

Synthesis of pharmaceutical intermediates, agrochemicals, and other fine chemicals.

Advantages

Versatile reactivity, potential pharmacological properties, and a valuable building block in organic chemistry for creating compounds with diverse applications.

InChI:InChI=1/C13H14N2O3/c1-13(2,3)18-12(17)15-11-5-4-9(8-16)6-10(11)7-14-15/h4-8H,1-3H3

Upstream product

• 253801-04-6 1H-indazole-5-carbaldehyde 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 943145-64-0 tert-butyl (Z)-5-(2-(benzyloxycarbonylamino)-3-methoxy-3-oxoprop-1-enyl)-1H-indazole-1-carboxylate 

Relevant articles and documents

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(Chemical Equation Presented) Amino acid esters 5-11 as tyrosine mimics have been synthesized in excellent enantioselectivity (up to 99.6% ee) and in good overall chemical yields. The key step in the sequence was the Burk's [Rh(COD)(2R,5R)-Et-DuPhos]BF4-catalyzed asymmetric hydrogenation of enamides with a variety of reactive functional groups.

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