635752-70-4

Basic information

• Product Name: N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-2-(4-hydroxy-benzyl)-N-methyl-benzenesulfonamide
• CAS NO: 635752-70-4
• Molecular Weight: 590.943
• Mol File: 635752-70-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-2-(4-hydroxy-benzyl)-N-methyl-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-2-(4-hydroxy-benzyl)-N-methyl-benzenesulfonamide(635752-70-4)
• EPA Substance Registry System: N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-2-(4-hydroxy-benzyl)-N-methyl-benzenesulfonamide(635752-70-4)

Safety Data

• Hazardous Substances Data: 635752-70-4(Hazardous Substances Data)

Upstream product

• 288161-85-3 N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-N-methyl-benzenesulfonamide 
• 288161-84-2 N-[1-butyl-1-(tert-butyl-dimethyl-silanyloxymethyl)-pentyl]-4-dimethylamino-benzenesulfonamide 
• 288161-83-1 N-(1-butyl-1-hydroxymethyl-pentyl)-4-dimethylamino-benzenesulfonamide 
• 288161-82-0 N-(1-butyl-1-hydroxymethyl-pentyl)-4-fluoro-benzenesulfonamide 
• 288161-81-9 di-n-butyl-ethanolamine 
• 35421-08-0 4-hydroxybenzyl chloride 

Downstream Products

• 635753-05-8 N-(1-butyl-1-formyl-pentyl)-4-dimethylamino-2-(4-hydroxy-benzyl)-N-methyl-benzenesulfonamide 

Relevant articles and documents

A novel class of apical sodium co-dependent bile acid transporter inhibitors: The 1,2-benzothiazepines

A series of 5-aryl-3,3-dibutyl-7-(dimethylamino)-1,2-benzothiazepin-4-ol 1,1-dioxides were prepared and were found to inhibit the apical sodium co-dependent bile acid transporter (ASBT) for the potential treatment for hyperlipidemia. Several 1,2-benzothiazepines exhibited low nanomolar in vitro activity. The synthesis and initial in vitro potency data is presented for this novel class of compounds.