635754-97-1

Basic information

• Product Name: (S)-1-(2-phenylethyl)-2-oxo-3-(tert-butoxycarbonylamino)-azepine
• Synonyms: (S)-1-(2-phenylethyl)-2-oxo-3-(tert-butoxycarbonylamino)-azepine
• CAS NO: 635754-97-1
• Molecular Weight: 332.443
• Mol File: 635754-97-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1-(2-phenylethyl)-2-oxo-3-(tert-butoxycarbonylamino)-azepine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(2-phenylethyl)-2-oxo-3-(tert-butoxycarbonylamino)-azepine(635754-97-1)
• EPA Substance Registry System: (S)-1-(2-phenylethyl)-2-oxo-3-(tert-butoxycarbonylamino)-azepine(635754-97-1)

Safety Data

• Hazardous Substances Data: 635754-97-1(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 21568-87-6 2-aminocaprolactam 
• 4455-09-8 2-phenylethyl tosylate 
• 76944-95-1 tert-butyl N-[(3S)-2-oxoazepan-3-yl]carbamate 

Downstream Products

• 209983-95-9 (S)-1-(2-phenylethyl)-2-oxo-3-amino-azepine 

Relevant articles and documents

Parallel liquid synthesis of N,N′-disubstituted 3-amino azepin-2-ones as potent and specific farnesyl transferase inhibitors

A rapid structure-activity study was performed by parallel liquid synthesis on N,N′-disubstitution of 3-amino azepin-2-one to afford potent and specific farnesyl transferase inhibitors with low nM enzymatic and cellular activities. The activities of the selected compounds were validated in vivo, and compounds 41a and 44a presented significant antitumour activity.