6362-66-9

Basic information

• Product Name: 2,3-Furandione, dihydro-4-phenyl-
• CAS NO: 6362-66-9
• Molecular Formula: C10H8O3
• Molecular Weight: 176.172
• Mol File: 6362-66-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,3-Furandione, dihydro-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Furandione, dihydro-4-phenyl-(6362-66-9)
• EPA Substance Registry System: 2,3-Furandione, dihydro-4-phenyl-(6362-66-9)

Safety Data

• Hazardous Substances Data: 6362-66-9(Hazardous Substances Data)

Usage

Physical state

white crystalline solid

Uses

precursor in the synthesis of pharmaceuticals and other organic compounds

Safety precautions

harmful if ingested, inhaled, or in contact with skin; recommended to use proper protective equipment and follow safety guidelines

Upstream product

• 478165-22-9 2-hydroxy-3-phenyl-but-3-enoic acid 
• 98-86-2 acetophenone 
• 91828-63-6 Methyl 2-hydroxy-3-phenyl-3-butenoate 
• 5441-04-3 3-methyl-3-phenyl-oxiranecarboxylic acid methyl ester 
• 50-00-0 formaldehyd 
• 99033-95-1 2-hydroxyimino-3-phenylpropanoic acid 
• 156-06-9 2-oxo-3-(phenyl)propionic acid 

Downstream Products

• 6476-23-9 3-acetoxy-4-phenyl-5H-furan-2-one 
• 6476-22-8 3-methoxy-4-phenyl-5H-furan-2-one 
• 492-38-6 2-phenylacrylic acid 
• 144-62-7 oxalic acid 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 65-85-0 benzoic acid 
• 100-42-5 styrene 
• 122-78-1 phenylacetaldehyde 

Relevant articles and documents

Design, synthesis, and evaluation of postulated transient intermediate and substrate analogues as inhibitors of 4-hydroxyphenylpyruvate dioxygenase

An epoxybenzoquinone, 4-hydroxyphenoxypropionic acid, and 2-hydroxy-3-phenyl-3-butenoic acid derivatives have been designed, synthesized, and evaluated for in vitro inhibition activity against 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) from pig liver by the spectrophotometric enol-borate method. The biological data demonstrated that neither epoxybenzoquinone ester nor 2-hydroxy-3-phenyl-3-butenoic acid is an inhibitor of 4-HPPD. The most potent 4-HPPD inhibitor tested was 3-hydroxy-4-phenyl-2(5H)-furanone with an IC50 value of 0.5 μM, which may serve as a lead compound for further design of more potent 4-HPPD inhibitors.