63625-56-9

Basic information

• Product Name: R(-)/S(+)-1,2-Propanediol
• Synonyms: R(-)/S(+)-1,2-Propanediol;1,2-Propylenglykol [german]
• CAS NO: 63625-56-9
• Molecular Formula: C3H8O2
• Molecular Weight: 76.09442
• Mol File: 63625-56-9.mol
• Article Data: 754

Chemical Properties

• Appearance: /
• CAS DataBase Reference: R(-)/S(+)-1,2-Propanediol(CAS DataBase Reference)
• NIST Chemistry Reference: R(-)/S(+)-1,2-Propanediol(63625-56-9)
• EPA Substance Registry System: R(-)/S(+)-1,2-Propanediol(63625-56-9)

Safety Data

• Hazardous Substances Data: 63625-56-9(Hazardous Substances Data)

Upstream product

• 97-64-3 ethyl 2-hydroxypropionate 
• 849585-22-4 LACTIC ACID 
• 50-70-4 D-sorbitol 
• 50-99-7 glucose 
• 556-52-5 oxiranyl-methanol 
• 116-09-6 hydroxy-2-propanone 
• 591-87-7 Allyl acetate 
• 503-30-0 trimethylene oxide 
• 7732-18-5 water 
• 57-50-1 Sucrose 
• 67-56-1 methanol 
• 7647-01-0 hydrogenchloride 
• 107-18-6 allyl alcohol 
• 7722-84-1 dihydrogen peroxide 

Downstream Products

• 4421-24-3 1-(2,4-dimethyl-[1,3]dioxolan-2-yl)-2-methyl-2-phenyl-propane 
• 108153-16-8 phosphoric acid-(2-hydroxy-phenyl ester)-(2-hydroxy-propyl ester) 
• 4359-32-4 trans-1-(2,4-dimethyl-[1,3]dioxolan-2-yl)-2-(2,6,6-trimethyl-cyclohex-2-enyl)-ethylene 
• 100073-30-1 1,2-propanediol ditosylate 
• 2927-26-6 <1,1,2-Trifluor-2-chlor-ethyl>-<2-benzoyloxy-propyl>-aether 
• 55983-39-6 2,7-dimethyl-5-phenyl-1,4,6,9-tetraoxa-5λ⁵-phospha-spiro[4.4]nonane 
• 93336-38-0 2-Cyclohexyloxy-4-methyl-<1.3.2>-dioxa-borolan 
• 7114-42-3 dimethyl-(4-methyl-[1,3,2]dioxaphospholan-2-yl)-amine 
• 6179-68-6 2-hexyloxy-4-methyl-[1,3,2]dioxaphospholane 
• 84549-34-8 2-isopropyl-4-methyl-1,3,2-dioxaphospholane-2-oxide 
• 14678-40-1 4-methyl-2-(N-phenylimino)-1,3-dioxolane 
• 89177-13-9 trans-2-(1-isobutoxycarbonyl-5-phenyl-7-ethylthiopyrrolo<3,2-d>pyrimidin-3-yl)-4-methyl-1,3-dioxolane 
• 89177-13-9 cis-2-(1-isobutoxycarbonyl-5-phenyl-7-ethylthiopyrrolo<3,2-d>pyrimidin-3-yl)-4-methyl-1,3-dioxolane 
• 79727-89-2 2-[4-(3,7-Dimethyl-oct-6-enyloxy)-phenyl]-2-ethyl-4-methyl-[1,3]dioxolane 

Relevant articles and documents

Tuning selectivity of Pt/CaCO3 in glycerol hydrogenolysis - A Design of Experiments approach

19 commercially available catalysts have been effectively screened in only 30 experiments for the hydrogenolysis of glycerol using a D-optimal design. Pt/CaCO3 emerged as both an active and selective catalyst and was studied in greater detail using a Central Composite Design. Upon addition of boric acid, the Pt/CaCO3 product selectivity could be changed from 1,2-propanediol towards lactic acid. The formation of 1,2-propanediol and lactic acid could be optimized by considering the Response Surface Model plots and formation pathways.

Hydrogenolysis of glycerol in an aqueous medium over Pt/WO3/zirconium phosphate catalysts studied by1H NMR spectroscopy

Bifunctional Pt/WO3/zirconium phosphate catalyzes the liquid-phase hydrogenolysis of glycerol in an aqueous medium.1H NMR spectroscopy (solvent suppression pulse program) is employed to monitor this reaction. Propanediols (1,3 + 1,2-PDO) formed as the major product along with propanols (1- and 2-POs) as the minor product. A synergistic enhancement in glycerol conversion and selectivity to 1,3-PDO was observed when both Pt and WO3were present in the catalyst. Avolcano-shapevariation of catalytic activity with W content was observed. A catalyst with 8 wt% W and 1 wt% Pt exhibited the highest selective hydrogenolysis performance (glycerol conversion = 92.3% and total PDOs selectivity = 45.9% and 1,3-PDO selectivity = 20.8% at 200 °C). Dispersed Pt in contact with polytungstate-type WO3species was found to be the active catalytic site.1H NMR spectroscopy is demonstrated as an attractive technique toquantifythe products of a glycerol hydrogenolysis reaction.

Sterically controlling 2-carboxylated imidazolium salts for one-step efficient hydration of epoxides into 1,2-diols

In order to overcome the disadvantages of excessive water and many byproducts in the conventional process of epoxide hydration into 1,2-diols, 2-carboxylated imidazolium salts were first adopted as efficient catalysts for one-step hydration of epoxides into 1,2-diols. By regulating the cation chain lengths, different steric structures of 2-carboxylated imidazolium salts with chain lengths from C1 to C4 were prepared. The salt with the shortest substituent chain (DMIC) exhibited better thermal stability and catalytic performance for hydration, achieving nearly 100% ethylene oxide (EO) conversion and 100% ethylene glycol (EG) selectivity at 120 °C, 0.5 h with just 5 times molar ratio of H2O to EO. Such a tendency is further confirmed and explained by both XPS analysis and DFT calculations. Compared with other salts with longer chains, DMIC has stronger interaction of CO2?anions and imidazolium cations, exhibiting a lower tendency to release CO2?and form HO-CO2?, which can nucleophilically attack and synergistically activate ring-opening of epoxides with imidazolium cations. The strong huge sterically dynamic structure ring-opening transition state slows down the side reaction, and both cations and anions stabilized the transition state imidazolium-EG-HO-CO2?, both of which could avoid excessive hydration into byproducts, explaining the high 1,2-diol yield. Based on this, the cation-anion synergistic mechanism is then proposed.