636992-58-0

Basic information

• Product Name: (E)-[2-cyano-4-(2-diethylcarbamoyl-1-methylvinyl)phenoxy]acetic acid ethyl ester
• Synonyms: (E)-[2-cyano-4-(2-diethylcarbamoyl-1-methylvinyl)phenoxy]acetic acid ethyl ester
• CAS NO: 636992-58-0
• Molecular Weight: 344.411
• Mol File: 636992-58-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-[2-cyano-4-(2-diethylcarbamoyl-1-methylvinyl)phenoxy]acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-[2-cyano-4-(2-diethylcarbamoyl-1-methylvinyl)phenoxy]acetic acid ethyl ester(636992-58-0)
• EPA Substance Registry System: (E)-[2-cyano-4-(2-diethylcarbamoyl-1-methylvinyl)phenoxy]acetic acid ethyl ester(636992-58-0)

Safety Data

• Hazardous Substances Data: 636992-58-0(Hazardous Substances Data)

Upstream product

• 40530-18-5 5-bromo-2-hydroxybenzonitrile 
• 39786-34-0 ethyl 2-(2-cyanophenoxy)acetate 
• 611-20-1 salicylonitrile 
• 1950-58-9 (E)-N,N-diethyl-2-butenamide 
• 328009-03-6 (4-bromo-2-cyanophenoxy)acetic acid ethyl ester 

Relevant articles and documents

Syntheses of 3-acetoacetylaminobenzo[b]furan derivatives having cysteinyl leukotriene 2 receptor antagonistic activity

Novel 3-acetoacetylaminobenzo[b]furan derivatives having a modified triene system at the 3-position were synthesized starting with 3-aminobenzo[b]furans. The enol isomers, 3-[(3-hydroxybul-2-enonyl)amino]benzo[b]furans (1), of the 3-acetoacetylaminobenzo[b]furans were obtained as stable isomers owing to formation of a hydrogen bonding between the enol hydroxyl group and the amidocarbonyl group. The planarity of the C-2 substituent through the C-3 side chain suggested the existence of a modified conjugational triene system in the enol compound. Cysteinyl leukotriene 1 and 2 receptor antagonistic activities for these compounds were evaluated. 2-(4-Cyanobenzoyl or ethoxycarbonyl)-3-[(2-cyano-3-hydroxybut-2-enonyl)amino]benzo[e]furans (15g, 15o, 15u) were moderately active.