6372-20-9

Basic information

• Product Name: diphenyl isobutylphosphoramidate
• Synonyms: diphenyl isobutylphosphoramidate
• CAS NO: 6372-20-9
• Molecular Weight: 305.313
• Mol File: 6372-20-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: diphenyl isobutylphosphoramidate(CAS DataBase Reference)
• NIST Chemistry Reference: diphenyl isobutylphosphoramidate(6372-20-9)
• EPA Substance Registry System: diphenyl isobutylphosphoramidate(6372-20-9)

Safety Data

• Hazardous Substances Data: 6372-20-9(Hazardous Substances Data)

Upstream product

• 108-95-2 phenol 
• 2524-64-3 chlorophosphoric acid diphenyl ester 
• 26386-88-9 diphenyl phosphoryl azide 
• 78-81-9 isobutylamine 
• 124900-92-1 isobutyl-amidophosphoryl chloride 

Relevant articles and documents

Substitution of diarylphosphoryl azides with aliphatic amines catalyzed by simple rare-earth metal salts: Efficient and novel preparation of phosphoryl amides

A novel and high efficient protocol was disclosed herein for the rare-earth metal salt-catalyzed substitution of phosphoryl azides with amines. In this homogeneous catalysis system, different diarylphosphoryl azides and aliphatic and aromatic amines were

Zinc-catalyzed transformation of diarylphosphoryl azides to diarylphosphate esters and amides

We have developed a facile and efficient procedure for the synthesis of diarylphosphate esters and amides. Using Zn(acac)2 as the catalyst, the reaction of diarylphosphoryl azides with aliphatic alcohols and phenols through an unusual P?N bond cleavage provided a number of diarylphosphate esters in good yields (22 examples, up to 94%). Additionally, various diarylphosphate amides were obtained from the corresponding amines in excellent yields as well (8 examples, up to 96%).

Reactivity of cage-like amines toward p-toluenesulfonyl chloride and diphenyl chlorophosphate in acetonitrile

The nucleophilic reactivity of amines of the norbornane, norbornene, and adamantane series toward p-toluenesulfonyl chloride and diphenyl chlorophosphate in acetonitrile at 25°C is determined mainly by the steric factor. Parameters characterizing spatial accessibility of the reaction center in the amine molecule have been determined. Cage-like substituents show no appreciable effect on the amine reactivity, as compared to common alkyl groups.