63768-13-8Relevant articles and documents
Using stereoretention for the synthesis of e -macrocycles with ruthenium-based olefin metathesis catalysts
Ahmed, Tonia S.,Montgomery, T. Patrick,Grubbs, Robert H.
, p. 3580 - 3583 (2018/04/12)
The synthesis of E-macrocycles is achieved using stereoretentive, Ru-based olefin metathesis catalysts supported by dithiolate ligands. Kinetic studies elucidate marked differences in activity among the catalysts tested, with catalyst 4 providing meaningful yields of products in much shorter reaction times than stereoretentive catalysts 2 and 3. Macrocycles were generated with excellent selectivity (>99% E) and in moderate to high yields (47-80% yield) from diene starting materials bearing two E-configured olefins. A variety of rings were constructed, ranging from 12- to 18-membered macrocycles, including the antibiotic recifeiolide.
A novel hydrogen transfer hydroalumination of alkenes with triisobutylaluminum catalyzed by Pd and other late transition metal complexes
Gagneur, Sebastien,Makabe, Hidefumi,Negishi, Ei-Ichi
, p. 785 - 787 (2007/10/03)
Hydrogen transfer hydroalumination of terminal alkenes and dienes can be achieved with 1.1 equiv. of (i-Bu)3Al and catalytic amounts of Cl2Pd(PPh3)2 and other late transition metal complexes containing Co, Rh, Ni, and Pt at ambient temperature in high yields.
