6378-11-6 Usage
Description
Chloridosulfurous acid ethyl ester, also known as Ethyl chlorosulfinate, is an inorganic compound derived from Thionyl Chloride. It possesses unique chemical properties that make it a versatile reagent in various chemical reactions and applications.
Uses
Used in Chemical Synthesis:
Chloridosulfurous acid ethyl ester is used as a chemical reagent for chlorination reactions, facilitating the introduction of chlorine into various organic and inorganic compounds.
Used in Pesticide Production:
In the agricultural industry, Chloridosulfurous acid ethyl ester is used as a key component in the production of biological agents, including insecticides and pesticides. Its reactivity and ability to form stable compounds make it a valuable asset in developing effective pest control solutions.
Used in Pharmaceutical Development:
Chloridosulfurous acid ethyl ester plays a crucial role in the preparation of pharmaceutical agents, such as CFTR potentiators. These potentiators are commonly used in the treatment of cystic fibrosis, a genetic disorder that affects the respiratory and digestive systems. Chloridosulfurous acid ethyl ester's versatility in chemical reactions allows for the development of targeted therapies that can improve the quality of life for patients with this condition.
Check Digit Verification of cas no
The CAS Registry Mumber 6378-11-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,7 and 8 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6378-11:
(6*6)+(5*3)+(4*7)+(3*8)+(2*1)+(1*1)=106
106 % 10 = 6
So 6378-11-6 is a valid CAS Registry Number.
InChI:InChI=1/C2H5ClO2S/c1-2-5-6(3)4/h2H2,1H3
6378-11-6Relevant articles and documents
Synthesis and Biological Evaluation of a Series of Novel Celastrol Derivatives with Amino Acid Chain
Pang, Chaohai,Luo, Jinhui,Liu, Chunhua,Wu, Xuejin,Wang, Dingyong
, (2018/05/04)
The synthesis of celastrol analogues containing amino acid ester at the C(29) position and their evaluation for cytotoxic activities in?vitro were reported. The MTT test showed that a set of derivatives with lower IC50 values than that of the positive control group cisplatin and the parent compound celastrol, which exhibited greater antiproliferative activities. The most potent title compounds 2a and 2e exhibited cytotoxic activities in?vitro against HeLa and A549 cell lines with IC50 values of 0.371 and 0.237?μm, 0.235 and 0.109?μm, respectively. The apoptosis assay demonstrated that 2a and 2e can induces of A549 cell apoptosis in low concentrations. These results showed that 2a and 2e may be promising for further research as antitumor agents.
On the esters of thiosulfurous acid.
ZINNER,KOELLING
, p. 284 - 291 (2007/10/05)
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