638-44-8

Basic information

• Product Name: N,N'-(dithiodiethylene)bisacetamide
• Synonyms: N,N'-(dithiodiethylene)bisacetamide
• CAS NO: 638-44-8
• Molecular Formula: C₈H₁₆N₂O₂S₂
• Molecular Weight: 236.35484
• EINECS: 211-338-5
• Mol File: 638-44-8.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N,N'-(dithiodiethylene)bisacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-(dithiodiethylene)bisacetamide(638-44-8)
• EPA Substance Registry System: N,N'-(dithiodiethylene)bisacetamide(638-44-8)

Safety Data

• Hazardous Substances Data: 638-44-8(Hazardous Substances Data)

Usage

General Description

N,N'-(dithiodiethylene)bisacetamide, also known as Bismate or Bis(2-acetamido-2-carboxyethyl) disulfide, is a chemical compound with the molecular formula C8H14N2O4S2. It is a water-soluble substance that is commonly used as a crosslinking agent in polymer chemistry and as a vulcanizing agent in rubber production. Its unique structure allows it to form strong covalent bonds between polymer chains, improving the strength, elasticity, and durability of various materials. Bismate is also used in the synthesis of pharmaceuticals, particularly as a reagent in the production of antibiotics and other medicinal compounds. Additionally, it has potential applications in the development of adhesives, coatings, and other advanced materials. However, it is important to handle this chemical with care, as it can be harmful if inhaled, ingested, or absorbed through the skin.

Upstream product

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Downstream Products

• 1190-73-4 2-(acetylamino)ethanethiol 
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Relevant articles and documents

Step-Economic Synthesis of Biomimetic β-Ketopolyene Thioesters and Demonstration of Their Usefulness in Enzymatic Biosynthesis Studies

Studies on the biosynthetic processing of polyene thioester intermediates are complicated by limited access to appropriate substrate surrogates. We present a step-economic synthetic access to biomimetic β-ketopolyene thioesters that is based on an Ir-catalyzed reductive Horner-Wadsworth-Emmons olefination. New β-ketotriene and pentaenethioates of pantetheine and N-acetylcysteamine were exemplarily synthesized via short and concise routes. The usefulness of these compounds was demonstrated in an in vitro assay with the ketoreductase domain MycKRB from mycolactone biosynthesis.

Characterization of the promiscuous: N-Acyl CoA transferase, LgoC, in legonoxamine biosynthesis

More than 500 siderophores are known to date, but only three were identified to be aryl-containing hydroxamate siderophores, legonoxamines A and B from Streptomyces sp. MA37, and aryl ferrioxamine 2 from Micrococcus luteus KLE1011. Siderophores are produced by microorganisms to scavenge iron from the environment, thereby making this essential metal nutrient available to the microbe. We demonstrate here that LgoC from MA37 is responsible for the key aryl-hydroxamate forming step in legonoxamine biosynthesis. Biochemical characterization established that LgoC displays considerable promiscuity for the acylation between N-hydroxy-cadaverine and SNAC (N-Acetylcysteamines) thioester derivatives.

CHIRAL CONTROL

The present invention relates to chirally controlled oligonucleotides, chirally controlled oligonucleotide compositions, and the method of making and using the same.