63980-78-9Relevant articles and documents
N-Terminal guanidine derivatives of teicoplanin antibiotics strongly active against glycopeptide resistant Enterococcus faecium
Sz?cs, Zsolt,Bereczki, Ilona,R?th, Erzsébet,Milánkovits, Márton,Ostorházi, Eszter,Batta, Gyula,Nagy, Lajos,Dombrádi, Zsuzsanna,Borbás, Anikó,Herczegh, Pál
, p. 603 - 614 (2020/05/19)
Antibiotic resistance is one of the major challenges in healthcare of our time. To meet this challenge, we designed and prepared guanidine and lipophilic guanidine derivatives of the glycopeptide antibiotic teicoplanin to armed them with activity against
A Tunable library of substituted thiourea precursors to metal sulfide nanocrystals
Hendricks, Mark P.,Campos, Michael P.,Cleveland, Gregory T.,Plante, Ilan Jen-La,Owen, Jonathan S.
, p. 1226 - 1230 (2015/06/22)
Controlling the size of colloidal nanocrystals is essential to optimizing their performance in optoelectronic devices, catalysis, and imaging applications. Traditional synthetic methods control size by terminating the growth, an approach that limits the reaction yield and causes batch-to-batch variability. Herein we report a library of thioureas whose substitution pattern tunes their conversion reactivity over more than five orders of magnitude and demonstrate that faster thiourea conversion kinetics increases the extent of crystal nucleation. Tunable kinetics thereby allows the nanocrystal concentration to be adjusted and a desired crystal size to be prepared at full conversion. Controlled precursor reactivity and quantitative conversion improve the batch-tobatch consistency of the final nanocrystal size at industrially relevant reaction scales.
