64036-06-2

Basic information

• Product Name: 4-Isoquinolinecarboxylic acid, 3-(1,3-benzodioxol-5-yl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-ox o-, trans-
• CAS NO: 64036-06-2
• Molecular Formula: C20H19NO7
• Molecular Weight: 385.373
• Mol File: 64036-06-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Isoquinolinecarboxylic acid, 3-(1,3-benzodioxol-5-yl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-ox o-, trans-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Isoquinolinecarboxylic acid, 3-(1,3-benzodioxol-5-yl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-ox o-, trans-(64036-06-2)
• EPA Substance Registry System: 4-Isoquinolinecarboxylic acid, 3-(1,3-benzodioxol-5-yl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-ox o-, trans-(64036-06-2)

Safety Data

• Hazardous Substances Data: 64036-06-2(Hazardous Substances Data)

Upstream product

• 63254-33-1 5-(methyliminomethyl)-1,3-benzodioxole 
• 5653-42-9 3,4-dimethoxyhomophthalic anhydride 
• 113975-93-2 N-[(1E)-1,3-benzodioxol-5-ylmethylene]methanamine 

Downstream Products

• 87922-31-4 N-methyl-3-<3,4-(methylenedioxy)phenyl>-6,7-dimethoxy-3,4-dihydro-1(2H)-isoquinoline 
• 87922-30-3 5,6-(methylenedioxy)-2-<2-(methylcarbamoyl)-4,5-dimethoxyphenyl>-1H-inden-1-one 

Relevant articles and documents

Synthesis and biological activity of structural analogues of the anticancer benzophenanthridine alkaloid nitidine chloride

The indenoisoquinoline analogue 9 of nitidine (1) has been prepared and found to possess significant anticancer activity against L1210 lymphoid leukemia, P388 lymphocytic leukemia, and B16 melanocarcinoma. Analogue 14, which lacks the B ring of nitidine (1), has also been synthesized. Compound 14 retains the in vitro toxicity associated with nitidine (1) but is devoid of antileukemic activity. The structural factors that may contribute to the difference in biological activity between the two closely related analogues 9 and 14 are discussed.