64049-49-6

Basic information

• Product Name: 3-(p-Formylphenoxy)-1,2-propanediol
• Synonyms: 3-(p-Formylphenoxy)-1,2-propanediol
• CAS NO: 64049-49-6
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 0
• Mol File: 64049-49-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 418.1°C at 760 mmHg
• Flash Point: 169.8°C
• Appearance: /
• Density: 1.278g/cm³
• Vapor Pressure: 9.71E-08mmHg at 25°C
• Refractive Index: 1.592
• CAS DataBase Reference: 3-(p-Formylphenoxy)-1,2-propanediol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(p-Formylphenoxy)-1,2-propanediol(64049-49-6)
• EPA Substance Registry System: 3-(p-Formylphenoxy)-1,2-propanediol(64049-49-6)

Safety Data

• Hazardous Substances Data: 64049-49-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H12O4/c11-5-8-1-3-9(4-2-8)14-10(6-12)7-13/h1-5,10,12-13H,6-7H2

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 96-24-2 3-monochloro-1,2-propanediol 
• 40663-68-1 4-(2-propenyloxy)benzaldehyde 
• 14697-49-5 4-(2,3-epoxy)propyloxybenzaldehyde 

Downstream Products

• 1194522-76-3 C₃₀H₂₄O₄ 
• 854111-05-0 (Z,Z)-5-[4-(2,3-dihydroxypropoxy)benzylidene]-2-isopropylimino-3-phenyl-thiazolidin-4-one 

Relevant articles and documents

Synthesis and biological evaluation of novel 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors

A series of novel 4-hydroxybenzaldehyde derivatives were synthesized and their inhibitory effects on the diphenolase activity of mushroom tyrosinase were investigated. Most of target compounds had more potent inhibitory activities than the parent compound 4-hydroxybenzaldehyde (IC50 = 1.22 mM). Interestingly, compound 3c bearing a dimethoxyl phosphate was found to be the most potent inhibitor with IC50 value of 0.059 mM. The inhibition kinetics analyzed by Lineweaver-Burk plots revealed that compound 3c was a non-competitive inhibitor (KI = 0.0368 mM). In particular, compound 3c showed no side effects at dose of 1600 mg/kg in mice. These results suggested that such compounds might be served as lead compounds for further designing new potential tyrosinase inhibitors.

5-(BENZ- (Z) -YLIDENE) -THIAZOLIDIN-4-ONE DERIVATIVES AS IMMUNOSUPPRESSANT AGENTS

The invention relates to pharmaceutical compositions containing at least one 5- (benz- (Z) -ylidene-thiazolidin-4-one derivative (I), to prevent or treat disorders associated with an activated immune system. Furthermore, the invention relates to novel thi