64146-63-0

Basic information

• Product Name: Benzene, 1-(1-heptynyl)-2-methyl-
• CAS NO: 64146-63-0
• Molecular Formula: C14H18
• Molecular Weight: 186.297
• Mol File: 64146-63-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(1-heptynyl)-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(1-heptynyl)-2-methyl-(64146-63-0)
• EPA Substance Registry System: Benzene, 1-(1-heptynyl)-2-methyl-(64146-63-0)

Safety Data

• Hazardous Substances Data: 64146-63-0(Hazardous Substances Data)

Upstream product

• 615-37-2 ortho-methylphenyl iodide 
• 627885-28-3 dimethyl-(1-heptynyl)silanol 
• 628-71-7 1-Heptyne 
• 627885-31-8 1-heptynyldimethylsilane 
• 5663-96-7 oct-2-ynoic acid 
• 16419-60-6 2-Methylphenylboronic acid 
• 98-80-6 phenylboronic acid 
• 1153648-13-5 chloro(hept-1-yn-1-yl)dimethylsilane 

Relevant articles and documents

Synthesis of Benzo[c]silole Derivatives Bearing a Tetrasubstituted Exocyclic C=C Double Bond by Palladium-Catalyzed Domino Reactions

The synthesis of diversely substituted 2,3-dihydro-benzo[c]siloles through an unprecedented palladium-catalyzed domino sequence is reported, involving a cyclocarbopalladation of an internal silylalkyne. This reaction proceeds with complete stereoselectivity to lead to a fully substituted exocyclic C=C double bond. Notably, the overall domino sequence appears to be crucial to obtain the desired cyclic vinylsilanes.

CuI/PPh3/PEG-Water: An efficient catalytic system for cross-coupling reaction of aryl iodides and alkynes

An efficient protocol for the copper-catalyzed Sonogashira coupling of aryl iodides with terminal acetylenes in water-polyethylene glycol has been established. Both electron-rich and electron-deficient aryl iodides were arylalkynated under microwave heating or reflux in oil bath to afford good to excellent yields. Copyright

Cross-Coupling of Alkynylsilanols with Aryl Halides Promoted by Potassium Trimethylsilanolate

The palladium-catalyzed cross-coupling of aliphatic alkynylsilanols with aryl iodides has been demonstrated with potassium trimethylsilanolate as the coupling promoter and copper(I) iodide as a cocatalyst. The cross-coupling proceeds at room temperature in good to excellent yield with a range of aryl iodides. A comparison of the reactivity of alkynylsilanols, trimethylsilylalkynes, and terminal alkynes under fluoride and fluoride-free conditions was performed to elucidate the role of silicon in the Sonogashira reaction.