64158-26-5

Basic information

• Product Name: 1,2-Ethanediol, 1,2-bis(2-methoxyphenyl)-
• CAS NO: 64158-26-5
• Molecular Formula: C16H18O4
• Molecular Weight: 274.317
• Mol File: 64158-26-5.mol
• Article Data: 30

Chemical Properties

• CAS DataBase Reference: 1,2-Ethanediol, 1,2-bis(2-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Ethanediol, 1,2-bis(2-methoxyphenyl)-(64158-26-5)
• EPA Substance Registry System: 1,2-Ethanediol, 1,2-bis(2-methoxyphenyl)-(64158-26-5)

Safety Data

• Hazardous Substances Data: 64158-26-5(Hazardous Substances Data)

Usage

Type

Resorcinol ether

Usage

Intermediate in the synthesis of pharmaceuticals and organic compounds

Physical state

White crystalline solid

Solubility

Insoluble in water, soluble in organic solvents

Applications

a. Cross-linking agent in polymer preparation
b. Production of benzimidazole antihistamines and other pharmaceuticals
c. Reagent in organic synthesis for producing a wide range of organic compounds

Upstream product

• 6706-96-3 2,2'-dimethoxybenzoin 
• 7664-93-9 sulfuric acid 
• 51608-60-7 N-(benzylidene)-p-methylbenzenesulfonamide 
• 108-24-7 acetic anhydride 
• 135-02-4 ortho-anisaldehyde 
• 250675-89-9 2-methoxyphenyl-α-(2-methoxyphenyl)-α-diazo-methyl carbinol 
• 89-95-2 2-methyl-benzyl alcohol 
• 74-88-4 methyl iodide 
• 53774-27-9 1,2-bis(2-methoxyphenyl)ethanol 
• 17601-37-5 (E)-2,2'-dimethoxystilbene 
• 612-16-8 (2-methoxyphenyl)methanol 
• 100-52-7 benzaldehyde 
• 75-46-7 trifluoromethan 

Downstream Products

• 860747-29-1 bis-(2-methoxy-phenyl)-acetaldehyde 
• 135-02-4 ortho-anisaldehyde 
• 4196-27-4 2,3-di(o-hydroxyphenylene)quinoxaline 
• 90833-61-7 2,3-bis(2-methoxyphenyl)-6-quinoxalinecarboxylic acid 
• 6706-92-9 2,2'-dimethoxybenzil 
• 183378-01-0 C₂₂H₁₇N₃O₄ 
• 1310679-65-2 C₂₃H₂₀N₂O₃ 
• 1310679-67-4 C₂₀H₁₄N₂O₃ 
• 579-75-9 2-Methoxybenzoic acid 
• 17601-37-5 1,2-bis(2-methoxyphenyl)ethene 

Relevant articles and documents

Metal-free thermal organocatalytic pinacol coupling of arylaldehydes using an isonicotinate catalyst with bis(pinacolato)diboron

The metal-free thermal organocatalytic pinacol coupling of arylaldehydes has been developed. The intermolecular coupling of arylaldehydes catalyzed byt-butyl isonicotinate with bis(pinacolato)diboron as the co-reducing agent afforded 1,2-diphenylethane-1,2-diols. This reaction was also applicable to the intramolecular coupling of 1,1′-biphenyl-2,2′-dicarbaldehydes to afford 9,10-dihydrophenanthrene-9,10-diols. Various functional groups were tolerated under this coupling condition.

Method for preparing intermediate of chiral vicinal diamine

The invention discloses a method for preparing an intermediate of chiral vicinal diamine. The method comprises the following steps: adding a compound IV into a solvent, stirring the compound IV and the solvent in an ice water bath, adding an initiator into the obtained reaction system, adding a reducing agent into the reaction system in batches, heating the reaction system to 20-80 DEG C, and stirring the reaction system; and extracting the reaction system after the reaction is completed, drying the obtained organic phase, filtering the dried organic phase, and performing rotary drying to obtain a compound V that is the intermediate. The preparation method of the invention has the advantages of simplicity and mild reaction conditions, and can be widely applied to industrial production.

Selective Pinacol Coupling on Regeneratable Supported Acids in Sole Water

Efficient pinacol coupling was developed in sole water, using a reusable heterogeneous supported acid source and zinc as cheap available metal source. This medium can be easily regenerated up to 10-fold without loss of activity. Moreover, supported acids enhance the selectivity of the pinacol coupling reaction compared with homogeneous acids.