64169-64-8 Usage
Description
[4-bromo-2-(hydroxymethyl)phenyl](4-fluorophenyl)methanone is a synthetic organic molecule characterized by its unique structure, featuring a benzophenone backbone with bromine and fluorine substituents. This ketone compound also includes a hydroxymethyl group, which is a hydroxyl (-OH) functional group attached to a carbon atom, further linking it to the aromatic ring. Its molecular formula is C14H10BrFO2, and due to its distinctive composition, it holds potential value in a range of chemical and pharmaceutical applications. However, further investigation and testing are necessary to fully comprehend its possible uses and reactivity.
Uses
Used in Chemical Synthesis:
[4-bromo-2-(hydroxymethyl)phenyl](4-fluorophenyl)methanone is used as an intermediate in the synthesis of various complex organic compounds. Its unique structure, including the bromine and fluorine substituents, makes it a valuable building block for creating novel molecules with specific properties and functions.
Used in Pharmaceutical Development:
In the pharmaceutical industry, [4-bromo-2-(hydroxymethyl)phenyl](4-fluorophenyl)methanone is used as a starting material for the development of new drugs. Its potential reactivity and the presence of functional groups make it a promising candidate for designing molecules with therapeutic applications, such as those targeting specific receptors or enzymes in the human body.
Used in Material Science:
[4-bromo-2-(hydroxymethyl)phenyl](4-fluorophenyl)methanone's unique structure and properties also make it a candidate for use in material science, where it could be employed in the development of new materials with specific characteristics, such as improved stability, reactivity, or other desirable properties.
Check Digit Verification of cas no
The CAS Registry Mumber 64169-64-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,1,6 and 9 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 64169-64:
(7*6)+(6*4)+(5*1)+(4*6)+(3*9)+(2*6)+(1*4)=138
138 % 10 = 8
So 64169-64-8 is a valid CAS Registry Number.
64169-64-8Relevant articles and documents
Novel and improved process for the preparation of citalopram
Reddy, M. Pulla,Bhujanga Rao,Usharani,Dubey
scheme or table, p. 1829 - 1832 (2012/01/13)
A novel process for the preparation of citalopram (1) has been described. The key intermediate 1-(4-fluorophenyl)-1,3-dihydroisobenzofuran- 5-carbonitrile (2) of citalopram is prepared using novel intermediates. The process involves simple acylation, hydrolysis and reduction, which can be easily adapted to commercial scale.
PROCESS AND INTERMEDIATES FOR PREPARING ESCITALOPRAM
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Page/Page column title page; 7-8; 1/4, (2008/06/13)
The antidepressant drug Escitalopram is prepared from 5-bromophthalide via the diol intermediate (4-bromo-2-(hydroxymethyl)phenyl)-(4-fluorophenyl)methanol. The racemic diol intermediate is converted to an enantiomerically enriched form by first converting the diol to a monoester intermediate and then reacting the monoester intermediate with an optically active acid, most preferably (+)-di-p-toluoyl tartaric acid, to form a salt. The salt is then crystallized to recover an enantiomerically enriched, crystalline form thereof. The monoester intermediate is preferably formed by reacting the racemic diol intermediate with an acid or a reactive acid derivative which, in a particularly preferred embodiment, is acetic anhydride.
