64262-23-3 Usage
Description
1-n-Propylpiperazine dihydrobromide is an organic compound that serves as an intermediate in the synthesis of various pharmaceuticals and chemical compounds. It is characterized by its unique structure, which includes a propyl group attached to a piperazine ring and two bromide ions. 1-n-Propylpiperazine dihydrobromide is known for its reactivity and ability to form a wide range of derivatives, making it a valuable building block in organic chemistry.
Uses
Used in Pharmaceutical Synthesis:
1-n-Propylpiperazine dihydrobromide is used as a key intermediate in the synthesis of amidines and sulfonamides of 5and 6-amino-2,3-bis(4-alkyl-1-piperazazinyl)quinoxalines. These compounds have potential applications in the development of new drugs and therapeutic agents, particularly in the treatment of various diseases and medical conditions.
In the synthesis process, 1-n-Propylpiperazine dihydrobromide reacts with other chemical compounds to form the desired amidines and sulfonamides. This reaction is crucial for the creation of new pharmaceutical agents with improved properties, such as enhanced efficacy, selectivity, and reduced side effects.
Overall, 1-n-Propylpiperazine dihydrobromide plays a significant role in the development of novel pharmaceuticals and chemical compounds, contributing to advancements in medicine and healthcare. Its versatility and reactivity make it an essential component in the synthesis of various organic compounds with potential applications in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 64262-23-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,2,6 and 2 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 64262-23:
(7*6)+(6*4)+(5*2)+(4*6)+(3*2)+(2*2)+(1*3)=113
113 % 10 = 3
So 64262-23-3 is a valid CAS Registry Number.
InChI:InChI=1S/C7H16N2.2BrH/c1-2-5-9-6-3-8-4-7-9;;/h8H,2-7H2,1H3;2*1H
64262-23-3Relevant articles and documents
Novel water-soluble sedative-hypnotic agents: Isoindolin-1-one derivatives
Kanamitsu, Norimasa,Osaki, Takashi,Itsuji, Yutaka,Yoshimura, Masakazu,Tsujimoto, Hisashi,Soga, Manabu
, p. 1682 - 1688 (2008/12/21)
We developed new intravenous sedative-hypnotic compounds with the isoindolin-1-one skeleton focusing on the water-soluble property and in vivo safety. We synthesized approximately 170 derivatives and evaluated their hypnotic effects by intravenous administration of the compounds to mice. A series of the 2-phenyl-3-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]isoindolin-1-one analogs, 3(-), 5(-), 27(-), and 47(-) [JM-1232(-)], showed potent sedative-hypnotic activity with good water solubility and a wide safety margin. The hypnotic doses (HD50s) of these 4 compounds when administered to mice were 2.35, 1.90, 2.17, and 3.12 mg/kg, respectively, and the lethal doses (LD50s) were 88.67, 64.69, >120, and >120 mg/kg, respectively. The therapeutic indexes (LD50/HD50) were 37.73, 34.05, >55.30, and >38.46, respectively. Among these compound, 47(-) [JM-1232(-)] is being considered as the most potential candidate for clinical trials in humans.
