643028-20-0

Basic information

• Product Name: dibenzyl (4R,5R)-1,3,2-dioxathiolane-4,5-dicarboxylate 2-oxide
• CAS NO: 643028-20-0
• Molecular Weight: 376.387
• Mol File: 643028-20-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: dibenzyl (4R,5R)-1,3,2-dioxathiolane-4,5-dicarboxylate 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: dibenzyl (4R,5R)-1,3,2-dioxathiolane-4,5-dicarboxylate 2-oxide(643028-20-0)
• EPA Substance Registry System: dibenzyl (4R,5R)-1,3,2-dioxathiolane-4,5-dicarboxylate 2-oxide(643028-20-0)

Safety Data

• Hazardous Substances Data: 643028-20-0(Hazardous Substances Data)

Upstream product

• 622-00-4 dibenzyl (2R,3R)-2,3-dihydroxybutanedioate 

Downstream Products

• 622-00-4 dibenzyl (2R,3R)-2,3-dihydroxybutanedioate 
• 128971-83-5 (2S,3R)-Dibenzyl 2-Azido-3-hydroxysuccinate 

Relevant articles and documents

An improved synthesis of aziridine-2,3-dicarboxylates via azido alcohols - Epimerization studies

The reasons for epimerization of 3-azido-2-hydroxysuccinates observed during the ring opening of epoxides or cyclic sulfites with sodium azide is now clarified. It is caused by the high acidity of the proton at the 3-position. This is proven by a proton deuterium exchange in assays with either D 2O or DCl containing solvents. The anti-3-azido-2-hydroxysuccinates serve as intermediates for enantiomerically pure trans-aziridine-2,3- dicarboxylates for which an optimized synthetic pathway is presented. The first example of an enantiomerically pure mixed diester of the aziridine-2,3- dicarboxylic acid the synthesis of the allyl ethyl ester is reported herein.