64315-36-2 Usage
Description
Different sources of media describe the Description of 64315-36-2 differently. You can refer to the following data:
1. Acetaminophen-d4 is intended for use as an internal standard for the quantification of acetaminophen ( | 22629) by GC- or LC-MS. Acetaminophen is an analgesic and antipyretic compound that inhibits COX-2 activity by more than 80%, albeit at relatively high doses, while it is less effective against COX-1. Acetaminophen-d4 is also available as an analytical reference standard
2. Acetaminophen-d4 (Item No. 22645) is an analytical reference material intended for use as an internal standard for the quantification of acetaminophen (Item Nos. 22629 | 10024) by GC- or LC-MS. Acetaminophen is categorized as an analgesic and antipyretic. Acetaminophen is reportedly used as a cutting agent in heroin (Item Nos. 9001543 | ISO60187). This product is intended for analytical forensic applications. This product is also available as a general research tool .
Chemical Properties
White Solid
Uses
Labelled Acetaminophen (A161220). Analgesic; antipyretic. 93% overall isotopic purity. A representative lot was 76% d4, 21% d3 and 2 % d2 with no detectable d0.
Check Digit Verification of cas no
The CAS Registry Mumber 64315-36-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,3,1 and 5 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 64315-36:
(7*6)+(6*4)+(5*3)+(4*1)+(3*5)+(2*3)+(1*6)=112
112 % 10 = 2
So 64315-36-2 is a valid CAS Registry Number.
64315-36-2Relevant articles and documents
Ortho-Selective Hydrogen Isotope Exchange of Phenols and Benzyl Alcohols by Mesoionic Carbene-Iridium Catalyst
Zhao, Liang-Liang,Wu, Yixin,Huang, Shiqing,Zhang, Zengyu,Liu, Wei,Yan, Xiaoyu
supporting information, p. 9297 - 9302 (2021/11/30)
Hydrogen isotope exchange reactions of phenols and benzyl alcohols have been achieved by a mesoionic carbene-iridium catalyst with high ortho selectivity and high functional group tolerance. Control experiments indicated that acetate is crucial to realize the ortho selectivity, whereas density functional theory calculations supported an outer-sphere direction with hydrogen bonding between acetate and the hydroxyl group.
Synthesis of labeled ambroxol and its major metabolites
Latli, Bachir,Hrapchak, Matt,Switek, Heinz-Karl,Retz, Daniel M.,Krishnamurthy, Dhileepkumar,Senanayake, Chris H.
experimental part, p. 15 - 23 (2010/04/26)
Ambroxol is a mucolytic agent used in the treatment of respiratory diseases. Herein, we report the synthesis of carbon-14-labeled ambroxol with the radioactive atom(s) either on the benzylic carbon or uniformly in the cyclohexyl ring with specific activities of 59 and 81 mCi/mmol, respectively. We also describe the preparation of deuterium-labeled ambroxol, its deuterium-labeled tetrahydroquinazoline metabolite (DHTQ), carbon-13-labeled 3,5-dibromoanthranilic acid metabolite, as well as an unlabeled O-glucuronide conjugate. Copyright
