64328-61-6

Basic information

• Product Name: 4-BUTOXYBENZOHYDRAZIDE
• Synonyms: 4-BUTOXYBENZOHYDRAZIDE;Nsc227237
• CAS NO: 64328-61-6
• Molecular Formula: C₁₁H₁₆N₂O₂
• Molecular Weight: 208.26
• Mol File: 64328-61-6.mol
• Article Data: 18

Chemical Properties

• Melting Point: 111-113 °C(Solv: benzene (71-43-2))
• Appearance: /
• Density: 1.093g/cm³
• Refractive Index: 1.535
• PKA: 12.66±0.10(Predicted)
• CAS DataBase Reference: 4-BUTOXYBENZOHYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BUTOXYBENZOHYDRAZIDE(64328-61-6)
• EPA Substance Registry System: 4-BUTOXYBENZOHYDRAZIDE(64328-61-6)

Safety Data

• Hazardous Substances Data: 64328-61-6(Hazardous Substances Data)

Usage

Description

4-BUTOXYBENZOHYDRAZIDE is a hydrazide chemical compound that serves as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is known for its potential to form complexes with metal ions, making it useful in various applications, including analytical chemistry, environmental remediation, and as a corrosion inhibitor in industrial settings. Furthermore, it has been studied for its antimicrobial and antifungal properties.

Uses

Used in Pharmaceutical and Agrochemical Industries:
4-BUTOXYBENZOHYDRAZIDE is used as a chemical intermediate for the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides.
Used in Analytical Chemistry:
4-BUTOXYBENZOHYDRAZIDE is used as a reagent for detecting and quantifying certain metal ions due to its ability to form complexes with them, which aids in analytical processes.
Used in Environmental Remediation:
4-BUTOXYBENZOHYDRAZIDE is utilized as a potential chelating agent for environmental remediation applications, helping to capture and remove metal ions from contaminated environments.
Used in Industrial Corrosion Inhibition:
4-BUTOXYBENZOHYDRAZIDE is used as a corrosion inhibitor in various industrial applications, protecting materials from degradation and extending their lifespan.
Used in Antimicrobial and Anti-Fungal Applications:
4-BUTOXYBENZOHYDRAZIDE has been studied for its antimicrobial and antifungal properties, which may be applied in controlling microbial growth across different industries, such as food preservation, water treatment, and healthcare.

InChI:InChI=1/C11H16N2O2/c1-2-3-8-15-10-6-4-9(5-7-10)11(14)13-12/h4-7H,2-3,8,12H2,1H3,(H,13,14)

Upstream product

• 4906-25-6 methyl 4-butyloxybenzoate 
• 5365-43-5 ethyl 4-butoxybenzoate 
• 1498-96-0 4-butoxybenzoic acid 
• 100256-94-8 4-propoxy-benzoic acid ethyl ester 
• 120-47-8 Ethyl 4-hydroxybenzoate 
• 99-76-3 methyl 4-hydroxylbenzoate 

Downstream Products

• 99857-20-2 4-butoxy-benzoyl azide 
• 865811-80-9 4-butoxy-benzoic acid N'-cyclopropanecarbonyl-hydrazide 
• 1065005-28-8 oxalyl acid N',N'-di(4-propyloxybenzoyl)-hydrazide 
• 250690-11-0 N-(4-bromobenzoyl)-N'-(4-butyloxybenzoyl)hydrazine 
• 1240520-25-5 4-decyloxybenzoic acid N-4-(butyloxy)benzoyl hydrazide 
• 1345861-04-2 3-acetyl-5-(4-n-butoxyphenyl)-2-(5-nitrothiophen-2-yl)-2,3-dihydro-1,3,4-oxadiazole 
• 1086096-29-8 2-(4-n-butoxyphenyl)-5-phenyl-1,3,4-oxadiazole 
• 876362-58-2 1-(p-butyloxyphenylcarbonyl)-2-phenylcarbonylhydrazine 
• 1609020-87-2 3-acetyl-5-(4-butoxy-phenyl)-2-(5-nitrofuran-2-yl)-2,3-dihydro-1,3,4-oxadiazole 
• 935559-47-0 4-butoxy-N’-((5-nitrofuran-2-yl)methylene)benzohydrazide 
• 1410633-49-6 C₁₂H₁₄N₂O₃ 
• 1630012-94-0 4-butyl-5-(4-butoxyphenyl)-2H-1,2,4-triazole-3(4H)-one 
• 901967-47-3 C₁₆H₂₅N₃O₃ 
• 1620200-73-8 diethyl (3-((5-(4-(n-butoxy)phenyl)-1H-1,2,4-triazol-3-yl)thio)propyl)phosphonate 

Relevant articles and documents

Synthesis, Antiproliferative and Antioxidant Activity of 3-Mercapto-1,2,4-Triazole Derivatives as Combretastatin A-4 Analogues

Two series of 3-mercapto-1,2,4-triazole derivatives containing alkoxy substituents different in size and position were synthesized and their structures were characterized by FT-IR, 1H NMR, 13C NMR spectroscopy and elemental analysis. The synthesized compounds were assessed for their antiproliferative activity against colon cancer cell line (SW480). The results indicated that the size and position of the alkoxy group significantly influenced the antiproliferative activity. The highest cancer cell growth inhibition values were observed for the compounds containing 3,4,5-trimethoxyphenyl groups in their structures (57.74, 54.14 and 60.70% at 50 μM for compounds 5a, 12b and 14, respectively). The synthesized compounds were also subjected to DPPH protocol for evaluating the antioxidant activity. The results showed that all compounds had moderate to high levels of antioxidant capacity as compared to ascorbic acid as standard, the highest free radical scavenging capacity of 75% was observed for compound 4a at 50 μM.

Development, characterisation and: In vitro evaluation of lanthanide-based FPR2/ALX-targeted imaging probes

We report the design, preparation and characterisation of three small-molecule, Formyl Peptide Receptor (FPR)-targeted lanthanide complexes (Tb·14, Eu·14 and Gd·14). Long-lived, metal-based emission was observed from the terbium complex (τH2/su

1-substituted benzoyl-4-fatty acyl semicarbazide derivative, preparation method and application thereof as antibacterial agent

The invention belongs to the technical field of antibacterial agents, and relates to a 1-substituted benzoyl-4-fatty acyl semicarbazide derivative, a preparation method and application thereof as an antibacterial agent. The compound is shown in a formula