64368-85-0

Basic information

• Product Name: 8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole
• Synonyms: 8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole;8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole(SALTDATA: FREE)
• CAS NO: 64368-85-0
• Molecular Formula: C₁₂H₁₃FN₂
• Molecular Weight: 204.2434232
• Mol File: 64368-85-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole(CAS DataBase Reference)
• NIST Chemistry Reference: 8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole(64368-85-0)
• EPA Substance Registry System: 8-fluoro-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole(64368-85-0)

Safety Data

• Hazardous Substances Data: 64368-85-0(Hazardous Substances Data)

Upstream product

• 1445-73-4 1-Methyl-4-piperidone 
• 823-85-8 4-fluorophenyhydrazine hydrochloride 
• 923293-16-7 4-fluoro-2-pyridin-3-ylphenylamine 
• 1296770-65-4 3-(2-azido-5-fluorophenyl)pyridine 
• 1296770-85-8 1-methyl-3-(2-azido-5-fluorophenyl)pyridinium triflate 
• 1296771-12-4 CF₃O₃S^(1-)*C₁₂H₁₀FN₂⁽¹⁺⁾ 
• 1003-98-1 2-bromo-4-fluoroaniline 
• 1692-25-7 3-pyridylboronic acid 

Downstream Products

• 1061352-77-9 2-methyl-5-[2-(pyridin-4-yl)ethyl]-8-fluoro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 
• 1208230-79-8 8-fluoro-5-[(Z)-1-methyl-2-phenylvinyl]-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 
• 1208230-76-5 8-fluoro-5-[(Z)-2-(4-fluorophenyl)vinyl]-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 
• 1208230-77-6 8-fluoro-2-methyl-5-[(Z)-2-(4-trifluoromethylphenyl)vinyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 
• 1061352-35-9 cis-2-methyl-5-(2-phenylethenyl)-8-fluoro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 
• 1061352-36-0 trans-2-methyl-5-(2-phenylethenyl)-8-fluoro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 
• 1061352-59-7 cis-2-methyl-5-[2-(4-methoxyphenyl)ethenyl]-8-fluoro-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 
• 1208230-75-4 8-fluoro-2-methyl-5-((Z)-2-(p-tolyl)vinyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 
• 1588498-22-9 N-(tert-butoxycarbonyl)-L-isoleucyl-N²-(2,4-dimethoxybenzyl)-N₁-{(1S)-2-[4-({[3-(8-fluoro-2-methyl-1,2,3,4-tetrahydro-5H-pyrido[4,3-b]indol-5-yl)propanoyl]oxy}methyl)-1H-1,2,3-triazol-1-yl]-1-methylethyl}-2-methylalaninamide 

Relevant articles and documents

Ruthenium-catalyzed γ-carbolinium ion formation from aryl azides; Synthesis of dimebolin

A range of γ-carbolines were produced stereoselectively from ruthenium(III)-catalyzed reactions of 3-pyridyl substituted aryl azides. Other catalysts and conditions were neither as selective nor as high-yielding. This method was used to synthesize dimebolin in a concise and efficient manner.