64415-11-8 Usage
Description
4,6-DICHLORO-2-METHYLTHIO-5-PHENYLPYRIMIDINE is a chemical compound characterized as a yellow crystalline powder or chunks. It is known for its role in the synthesis of various catalysts, particularly those derived from cinchona alkaloids.
Uses
Used in Pharmaceutical Industry:
4,6-DICHLORO-2-METHYLTHIO-5-PHENYLPYRIMIDINE is used as a key intermediate in the synthesis of cinchona alkaloid-derived catalysts for [application reason]. These catalysts are essential in various pharmaceutical applications, including the production of enantiomerically pure compounds, which are crucial in the development of many drugs.
Used in Chemical Synthesis:
In the field of chemical synthesis, 4,6-DICHLORO-2-METHYLTHIO-5-PHENYLPYRIMIDINE is used as a building block for the creation of more complex molecules. Its unique structure allows for further functionalization and modification, making it a valuable component in the synthesis of various organic compounds.
Used in Research and Development:
4,6-DICHLORO-2-METHYLTHIO-5-PHENYLPYRIMIDINE is also utilized in research and development settings, where it serves as a model compound for studying the properties and reactivity of similar pyrimidine-based structures. This helps scientists understand the underlying mechanisms of various chemical reactions and develop new synthetic strategies.
Used in Analytical Chemistry:
4,6-DICHLORO-2-METHYLTHIO-5-PHENYLPYRIMIDINE's distinct chemical properties make it suitable for use in analytical chemistry as a reference material or a standard for the calibration of analytical instruments. Its yellow crystalline nature allows for easy identification and handling, making it a reliable choice for such applications.
Biochem/physiol Actions
4,6-Dichloro-2-methylthio-5-phenylpyrimidine has significant in vivo antinflammatory activity.
Check Digit Verification of cas no
The CAS Registry Mumber 64415-11-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,4,1 and 5 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 64415-11:
(7*6)+(6*4)+(5*4)+(4*1)+(3*5)+(2*1)+(1*1)=108
108 % 10 = 8
So 64415-11-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H8Cl2N2S/c1-16-11-14-9(12)8(10(13)15-11)7-5-3-2-4-6-7/h2-6H,1H3
64415-11-8Relevant articles and documents
Convenient synthesis of 2-(methylsulfonyl)pyrimidine derivatives
Huang, Tong-Hui,Zhou, Shan-Shan,Wu, Xin,An, Lin,Yin, Xiao-Xing
, p. 714 - 720 (2018/02/16)
An efficient and convenient approach for the preparation of functionalized 2-(methylsulfonyl)pyrimidine derivatives has been developed through cyclic condensation of malonate derivatives with S-methylisothiouronium sulfate followed by derivation and oxidation in water–acetone mixture using oxone as the oxidant. This synthetic strategy provides an efficient and environmentally friendly approach for easy access to 2-(methylsulfonyl)pyrimidine derivatives with considerable yields.
