64625-55-4

Basic information

• Product Name: 19(R)-HYDROXY PROSTAGLANDIN E1
• Synonyms: 9-OXO-11ALPHA,15S,19R-TRIHYDROXY-PROST-13E-EN-1-OIC ACID;19(R)-HYDROXY PROSTAGLANDIN E1;19(R)-hydroxy Prostaglandin E1;QVVXWHIDRKRPMO-VOSXNNSYSA-N;19(R)-hydroxy PGE1;9-oxo-11α,15S,19R-trihydroxy-prost-13E-en-1-oic acid
• CAS NO: 64625-55-4
• Molecular Formula: C20H34O6
• Molecular Weight: 370.48
• Mol File: 64625-55-4.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 19(R)-HYDROXY PROSTAGLANDIN E1(CAS DataBase Reference)
• NIST Chemistry Reference: 19(R)-HYDROXY PROSTAGLANDIN E1(64625-55-4)
• EPA Substance Registry System: 19(R)-HYDROXY PROSTAGLANDIN E1(64625-55-4)

Safety Data

• Hazardous Substances Data: 64625-55-4(Hazardous Substances Data)

Usage

Description

19(R)-Hydroxy Prostaglandin E1 (19(R)-OH PGE1) is the primary prostaglandin found in the semen of primates, including humans. It acts as an agonist for the EP1 and EP3 receptor subtypes and demonstrates contractile activity on smooth muscle preparations. This bioactive molecule has a unique role in modulating physiological processes and holds potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
19(R)-Hydroxy Prostaglandin E1 is used as a therapeutic agent for its contractile effects on smooth muscle tissues. Its agonistic activity on EP1 and EP3 receptor subtypes makes it a valuable compound for the development of drugs targeting specific physiological responses.
Used in Smooth Muscle Contraction Research:
In the field of smooth muscle research, 19(R)-Hydroxy Prostaglandin E1 is used as a research tool to study the mechanisms of smooth muscle contraction. Its EC50 values of 320 nM for contracting guinea pig ileum (expressing EP1 receptors) and 80 nM for contracting chick ileum (expressing EP3 receptors) provide insights into the potency and receptor specificity of this prostaglandin.
Used in Reproductive Biology Studies:
19(R)-Hydroxy Prostaglandin E1, being a major component of primate semen, is used in reproductive biology studies to understand its role in fertility and reproductive health. Its presence in semen and its effects on smooth muscle may contribute to the overall reproductive process.