64747-69-9

Basic information

• Product Name: Benzamide, 4-(fluoromethyl)-
• CAS NO: 64747-69-9
• Molecular Formula: C8H8FNO
• Molecular Weight: 153.156
• Mol File: 64747-69-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzamide, 4-(fluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 4-(fluoromethyl)-(64747-69-9)
• EPA Substance Registry System: Benzamide, 4-(fluoromethyl)-(64747-69-9)

Safety Data

• Hazardous Substances Data: 64747-69-9(Hazardous Substances Data)

Upstream product

• 58914-40-2 4-(bromomethyl)benzamide 
• 619-55-6 para-methylbenzamide 
• 1309-60-0 lead(IV) oxide 

Downstream Products

• 64747-70-2 4-(difluoromethyl)benzamide 

Relevant articles and documents

Transition-metal-free C-H oxidative activation: Persulfate-promoted selective benzylic mono- and difluorination

An operationally simple and selective method for the direct conversion of benzylic C-H to C-F to obtain mono- and difluoromethylated arenes using Selectfluor as a fluorine source is developed. Persulfate can be used to selectively activate benzylic hydrogen atoms toward C-F bond formation without the aid of transition metal catalysts.

Fluorination process

Aromatic compounds containing an α-fluoroalkyl or α,α-difluoroalkyl side chain are prepared by reacting selected aromatic compounds with a mixture of HF and a metal oxide which is PbO2 or NiO2 at -30° to +80° C. Exemplary is the conv