647853-32-5 Usage
General Description
3-(2-Hydroxyethyl)benzeneboronic acid is a boronic acid compound with a molecular formula of C8H11BO4. It contains a benzene ring and a boronic acid functional group with an attached hydroxyethyl group. It is commonly used as a reagent in organic synthesis reactions due to its ability to form stable and reversible complexes with diols, including sugars and amino alcohols. 3-(2-Hydroxyethyl)benzeneboronic acid has been utilized in the development of pharmaceuticals, agrochemicals, and materials science. It is also being studied for its potential application in the treatment of diabetes and cancer, as well as in the field of molecular sensors and detection.
Check Digit Verification of cas no
The CAS Registry Mumber 647853-32-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,7,8,5 and 3 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 647853-32:
(8*6)+(7*4)+(6*7)+(5*8)+(4*5)+(3*3)+(2*3)+(1*2)=195
195 % 10 = 5
So 647853-32-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H11BO3/c10-5-4-7-2-1-3-8(6-7)9(11)12/h1-3,6,10-12H,4-5H2
647853-32-5Relevant articles and documents
Design and synthesis of novel meta-linked phenylglycine macrocyclic FVIIa inhibitors
Richter, Jeremy M.,Cheney, Daniel L.,Bates, J. Alex,Wei, Anzhi,Luettgen, Joseph M.,Rendina, Alan R.,Harper, Timothy M.,Narayanan, Rangaraj,Wong, Pancras C.,Seiffert, Dietmar,Wexler, Ruth R.,Priestley, E. Scott
supporting information, p. 67 - 72 (2017/12/12)
Two novel series of meta-linked phenylglycine-based macrocyclic FVIIa inhibitors have been designed to improve the rodent metabolic stability and PK observed with the precursor para-linked phenylglycine macrocycles. Through iterative structure-based design and optimization, the TF/ FVIIa Ki was improved to subnanomolar levels with good clotting activity, metabolic stability, and permeability.