647863-01-2

Basic information

• Product Name: 7-benzyl-4-chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine
• Synonyms: 7-benzyl-4-chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine
• CAS NO: 647863-01-2
• Molecular Formula: C₁₅H₁₃ClF₃N₃
• Molecular Weight: 327.73
• Product Categories: CHIRAL CHEMICALS
• Mol File: 647863-01-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 355.9 °C at 760 mmHg
• Flash Point: 169.1 °C
• Appearance: /
• Density: 1.379 g/cm³
• Vapor Pressure: 3.03E-05mmHg at 25°C
• Refractive Index: 1.563
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 3.92±0.20(Predicted)
• CAS DataBase Reference: 7-benzyl-4-chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-benzyl-4-chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine(647863-01-2)
• EPA Substance Registry System: 7-benzyl-4-chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine(647863-01-2)

Safety Data

• Hazardous Substances Data: 647863-01-2(Hazardous Substances Data)

Usage

General Description

7-benzyl-4-chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine is a chemical compound with potential applications in the field of pharmaceuticals. It is a heterocyclic compound that contains a pyrimidine ring and a tetrahydropyrido moiety. The benzyl and chloro groups, as well as the trifluoromethyl substituent, add specific chemical properties to the molecule. 7-benzyl-4-chloro-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine has shown potential for various biological activities, including antiviral and anticancer properties. Its unique structure makes it an interesting candidate for further research and potential drug development.

InChI:InChI=1/C15H13ClF3N3/c16-13-11-6-7-22(8-10-4-2-1-3-5-10)9-12(11)20-14(21-13)15(17,18)19/h1-5H,6-9H2

Upstream product

• 647862-97-3 7-benzyl-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-ol 

Downstream Products

• 647863-02-3 2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride 
• 647863-05-6 4-methoxy-7-(phenylmethyl)-2-(trifluoromethyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine 

Relevant articles and documents

AMINOCYCLOHEXANES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES

The present invention is directed to novel substituted aminocyclohexanes which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DPP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.

PIPERIDINO PYRIMIDINE DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OF DIABETES

The present invention is directed to compounds which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.