64798-32-9

Basic information

• Product Name: Benzenamine, 3-chloro-N-2-propynyl-
• CAS NO: 64798-32-9
• Molecular Formula: C9H8ClN
• Molecular Weight: 165.622
• Mol File: 64798-32-9.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzenamine, 3-chloro-N-2-propynyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 3-chloro-N-2-propynyl-(64798-32-9)
• EPA Substance Registry System: Benzenamine, 3-chloro-N-2-propynyl-(64798-32-9)

Safety Data

• Hazardous Substances Data: 64798-32-9(Hazardous Substances Data)

Upstream product

• 108-42-9 3-chloro-aniline 
• 659-86-9 propargyl iodide 
• 34646-10-1 propargyl p-nitrobenzenesulphonate 
• 20569-03-3 propargyl m-nitrobenzenesulphonate 
• 34646-08-7 3-Chlor-phenylsulfonsaeure-propargylester 
• 6165-76-0 propargyl p-toluenesulfonate 
• 6165-75-9 propargyl benzenesulfonate 
• 106-96-7 propargyl bromide 
• 624-65-7 2-propynyl chloride 

Downstream Products

• 1616405-61-8 N-methyl-N-(prop-2-yn-1-yl)-(3-chlorophenyl)amine 
• 1092371-31-7 9-{4-[(3-chloro-phenylamino)-methyl]-[1,2,3]triazol-1-yl}-5-(4-hydroxy-3,5-dimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 1092371-30-6 9-{4-[(3-chloro-phenylamino)-methyl]-[1,2,3]triazol-1-yl}-5-(3,4,5-trimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 64796-24-3 1-(3-Chloro-phenyl)-3-[1-(3-chloro-phenyl)-1-methyl-ethyl]-1-prop-2-ynyl-urea 

Relevant articles and documents

Anti-methicillin resistant Staphylococcus aureus activity, synergism with oxacillin and molecular docking studies of metronidazole-triazole hybrids

MRSA causes 60-70% of Staphylococcus aureus infection in hospitals and it has developed resistance against the currently available drugs. Interestingly, a series of 35 metronidazole-triazole hybrids on screening against MRSA were found to be active. Compound 22 was found to be effective at 4 μg/mL concentration against nine strains of MRSA. The inhibitory activity was further enhanced upto 1 μg/mL when this compound was used in combination with oxacillin in 1:1 ratio. All the compounds were found to be non-toxic in THP-1 cell line upto a concentration of 50 μM. The time-kill kinetics studies suggested bacteriostatic nature of the compounds. In silico studies show that these compounds interact with Thr600, Ser598, Asn464, His583 and Tyr446 in the active site of PBP2a crystal structure from MRSA.

Synthesis and Activity of 1,2,3-Triazole Aminopyrimidines against Cyanobacteria as PDHc-E1 Competitive Inhibitors

Cyanobacteria harmful algal blooms are of global concern, but all currently available algicides in the market are nonselective and have potential side effects on nontarget species. In the present work, two series of compounds (4 and 6) comprising 16 novel

Stereospecific Ring Opening and Cycloisomerization of Aziridines with Propargylamines: Synthesis of Functionalized Piperazines and Tetrahydropyrazines

Stereospecific Cu-catalyzed nucleophilic ring opening of N-sulfonylaziridines with propargylamines and subsequent hydroamination afford piperazines, which leads to double-bond isomerization to furnish tetrahydropyrazines. Optically active aziridines can be cross-coupled with high enantiomeric purities (>98% ee).