64818-80-0

Basic information

• Product Name: Benzoic acid, 2-amino-4-methyl-, ethyl ester
• Synonyms: 2-amino-4-methyl-benzoic acid ethyl ester;Benzoic acid,2-amino-4-methyl-,ethyl ester;2-Amino-4-methyl-benzoesaeure-aethylester;Ethyl-4-methylanthranilat
• CAS NO: 64818-80-0
• Molecular Formula: C10H13NO2
• Molecular Weight: 179.219
• Mol File: 64818-80-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-amino-4-methyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-amino-4-methyl-, ethyl ester(64818-80-0)
• EPA Substance Registry System: Benzoic acid, 2-amino-4-methyl-, ethyl ester(64818-80-0)

Safety Data

• Hazardous Substances Data: 64818-80-0(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 2305-36-4 4-methylanthranilic acid 
• 113861-67-9 4-methyl-2-nitrobenzoic acid ethyl ester 
• 1128-47-8 6-methylindoline-2,3-dione 

Downstream Products

• 106976-24-3 2-amino-5-bromo-4-methylbenzoic acid 
• 79043-90-6 ethyl 2-acetamido-4-methylbenzoate 

Relevant articles and documents

Overcoming the Deallylation Problem: Palladium(II)-Catalyzed Chemo-, Regio-, and Stereoselective Allylic Oxidation of Aryl Allyl Ether, Amine, and Amino Acids

We report herein a Pd(II)/bis-sulfoxide-catalyzed intramolecular allylic C-H acetoxylation of aryl allyl ether, amine, and amino acids with the retention of a labile allyl moiety. Mechanistically, the reaction proceeds through a distinct double-bond isomerization from the allylic to the vinylic position followed by intramolecular carboxypalladation and the β-hydride elimination pathway. For the first time, C-H oxidation of N-allyl-protected amino acids to furnish five-membered heterocycles through 1,3-syn-addition is established with excellent diastereoselectivity.

Quinazolinone and isoquinolinone derivative

The present invention relates to quinazolinone and isoquinolinone derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.