6486-05-1

Basic information

• Product Name: Methylselenol
• Synonyms: Methylselenol;Methyl selenomercaptan;Monomethylselenol;Selenomethanol;Methylselenol,95%
• CAS NO: 6486-05-1
• Molecular Formula: CH₄Se
• Molecular Weight: 95.00246
• Mol File: 6486-05-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 207 °C(Solv: water (7732-18-5))
• Boiling Point: 12 °C(Press: 758 Torr)
• Appearance: Liquid - stench!
• PKA: 6.50±0.70(Predicted)
• Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
• CAS DataBase Reference: Methylselenol(CAS DataBase Reference)
• NIST Chemistry Reference: Methylselenol(6486-05-1)
• EPA Substance Registry System: Methylselenol(6486-05-1)

Safety Data

• Hazardous Substances Data: 6486-05-1(Hazardous Substances Data)

Usage

Description

Methylselenol is an organoselenium compound that serves as a selenium analogue of methanol, characterized by a methyl group covalently bound to a selenol group. It is a liquid with a strong, unpleasant odor.

Uses

Used in Pharmaceutical Industry:
Methylselenol is used as a pharmaceutical compound for its potential therapeutic properties. Due to its selenium content, it may exhibit antioxidant and anti-inflammatory effects, which can be beneficial in the treatment of various diseases and conditions.
Used in Chemical Synthesis:
Methylselenol can be utilized as a reagent or intermediate in the synthesis of various organic compounds, particularly those involving selenium. Its unique chemical properties make it a valuable component in the development of new molecules with specific applications.
Used in Agriculture:
In the agricultural sector, Methylselenol may be employed as a component in the development of biopesticides or as a supplement to enhance the selenium content in crops, which can improve their nutritional value and contribute to better overall health in humans and animals.
Used in Environmental Applications:
Methylselenol could potentially be used in environmental applications, such as the remediation of selenium-contaminated sites or the treatment of wastewater to remove selenium compounds, thus reducing their harmful effects on ecosystems and human health.
Used in Nanotechnology:
In the field of nanotechnology, Methylselenol may find applications in the synthesis of selenium-based nanoparticles or nanowires, which could have potential uses in electronics, energy storage, and other advanced materials.

Upstream product

• 7101-31-7 dimethyl diselenide 
• 76573-17-6 α-(methylseleno)-p-nitrostyrene 
• 62782-96-1 3,4-Bis(methylseleno)cyclobuten-1,2-dion 
• 54194-80-8 μ-methylselenodiborane(6) 
• 7732-18-5 water 
• 1255907-92-6 methyl N,N'-di(fur-2-ylcarbonyl)-imidoselenocarbamate 
• 1255907-94-8 methyl N,N'-di(3-chlorothien-2-ylcarbonyl)-imidoselenocarbamate 

Downstream Products

• 7101-31-7 dimethyl diselenide 
• 66622-20-6 trimethyl orthoselenoformate 
• 144090-34-6 Cyclohexanon-dimethylselenoketal 
• 59345-45-8 2-Methylselanyl-1-phenyl-octan-1-one 
• 5925-66-6 methyl benzoselenoate 
• 56051-04-8 1,1-bis(methylseleno)ethane 
• 71518-69-9 1,1-bis(methylseleno)-4-tert-butyl cyclohexane 
• 56051-06-0 2,2-propane 
• 59554-56-2 (E)-3,4-Dimethyl-4-methylselanyl-1-phenyl-pent-1-en-3-ol 
• 42057-99-8 2-methylselanyl-cyclohex-1-enecarbaldehyde 
• 119353-08-1 1,1,3-Tris-methylselanyl-cyclohexane 
• 119353-17-2 3-Methyl-3-methylselanyl-cyclohexanone 
• 119353-16-1 1,3-Bis(methylseleno)-3-methyl-1-cyclohexene 
• 119353-11-6 1,1-Bis(methylseleno)-3-methyl-2-cyclohexene 

Relevant articles and documents

Structural variations on antitumour agents derived from bisacylimidoselenocarbamate. A proposal for structure-activity relationships based on the analysis of conformational behaviour

A molecular modelling study has been carried out on a previously reported series of symmetrically substituted bisacylimidoselenocarbamate (BSeC) derivatives that show remarkable antitumour activity in vitro against a panel of human tumour cell lines. These derivatives can be considered as a central scaffold constructed around a methyl carbamimidoselenoate nucleus in which two heteroarylacyl fragments are located on the scaffold nitrogen atoms, thus forming the different BSeCs. The results reveal that the nature of the selected heteroaryl ring has a marked influence on the antiproliferative activity of the compounds and this can be related, as a first approximation, to the ability to release methylselenol (MeSeH), a compound that, according to our initial hypothesis, is ultimately responsible for the antitumour activity of the compounds under investigation. The release of MeSeH from the active BSeCs has been confirmed by means of Head Space Gas Chromatography Mass Spectrometry techniques. The data that support this connection include the topography of the molecules, the conformational behaviour of the compounds, which influences the accessibility of the hydrolysis point, the interaction map obtained for an O2H type probe, and the location and energy of the HOMO/LUMO orbitals.

Gas Phase Reactions, 23. Thermal decomposition of Open-Chain Dialkyl Sulfides, Disulfides and Diselenides

The thermal decomposition of the dialkyl chalcogenide derivatives RSR, RSSR and RSeSeR (R = CH3, CH2CH3, CH2CH2CH3, CH(CH3)2, C(CH3)3) in a heated flow tube is analyzed and optimized using PE spectroscopy.Whereas high-temperature pyrolysis >1000 K yields mixtures of thermodynamically favored final products like H2, CH4, CS2, and HCCH, the lowest thermal reaction channel produces homogeneously olefin, H2S, and sulfur or olefin, alkaneselenol, H2Se, and selenium, respectively.The decomposition temperatures increase from RSeSeR via RSSR towards RSR and also with decreasing size of the alkyl groups.Based on the experimental data the possible course of the thermal decomposition is discussed.