648888-69-1

Basic information

• Product Name: 4'-trifluoromethyl-biphenyl-4-carboxylic acid [4-(4-{4-ethyl-2-[2-(tetrahydro-pyran-2-yloxy)-ethoxy]-phenyl}-piperidin-1-yl)-butyl]-amide
• Synonyms: 4'-trifluoromethyl-biphenyl-4-carboxylic acid [4-(4-{4-ethyl-2-[2-(tetrahydro-pyran-2-yloxy)-ethoxy]-phenyl}-piperidin-1-yl)-butyl]-amide
• CAS NO: 648888-69-1
• Molecular Weight: 652.797
• Mol File: 648888-69-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4'-trifluoromethyl-biphenyl-4-carboxylic acid [4-(4-{4-ethyl-2-[2-(tetrahydro-pyran-2-yloxy)-ethoxy]-phenyl}-piperidin-1-yl)-butyl]-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-trifluoromethyl-biphenyl-4-carboxylic acid [4-(4-{4-ethyl-2-[2-(tetrahydro-pyran-2-yloxy)-ethoxy]-phenyl}-piperidin-1-yl)-butyl]-amide(648888-69-1)
• EPA Substance Registry System: 4'-trifluoromethyl-biphenyl-4-carboxylic acid [4-(4-{4-ethyl-2-[2-(tetrahydro-pyran-2-yloxy)-ethoxy]-phenyl}-piperidin-1-yl)-butyl]-amide(648888-69-1)

Safety Data

• Hazardous Substances Data: 648888-69-1(Hazardous Substances Data)

Upstream product

• 648888-67-9 4-(4-{4-ethyl-2-[2-(tetrahydro-pyran-2-yloxy)-ethoxy]-phenyl}-piperidin-1-yl)-butylamine 
• 195457-71-7 4-[4-(trifluoromethyl)phenyl]benzoic acid 

Relevant articles and documents

ARYL PIPERIDINE DERIVATIVES AND USE THEREOF TO REDUCE ELEVATED LEVELS OF LDL-CHOLESTEROL

This invention relates to novel compounds which up-regulate LDL receptor (LDL-r) expression and to processes for their preparation, pharmaceutical compositions containing them and their medical use. More particularly, this invention relates to novel aromatic piperidines and their use in therapy.