64890-22-8

Basic information

• Product Name: 4-Pyridinamine, N-methyl-N-phenyl-
• CAS NO: 64890-22-8
• Molecular Formula: C12H12N2
• Molecular Weight: 184.241
• Mol File: 64890-22-8.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: 4-Pyridinamine, N-methyl-N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyridinamine, N-methyl-N-phenyl-(64890-22-8)
• EPA Substance Registry System: 4-Pyridinamine, N-methyl-N-phenyl-(64890-22-8)

Safety Data

• Hazardous Substances Data: 64890-22-8(Hazardous Substances Data)

Upstream product

• 872-85-5 pyridine-4-carbaldehyde 
• 620-08-6 4-methoxypyridine 
• 100-61-8 N-methylaniline 
• 504-24-5 4-aminopyridine 
• 626-61-9 4-Chloropyridine 
• 1120-87-2 4-bromopyridin 
• 1413439-80-1 C₁₂H₂₀N₂O₂Si 
• 1413439-93-6 C₉H₁₂N₂O₂ 
• 109-00-2 3-HYDROXYPYRIDINE 
• 71366-41-1 4'-Oxo-4'H-[1,1']bipyridinyl-1-ylium; chloride 
• 100-48-1 pyridine-4-carbonitrile 
• 7379-35-3 4-chlorpyridine hydrochloride 
• 4783-86-2 4-phenoxypyridine 
• 2739-12-0 N-methylaniline hydrochloride 

Relevant articles and documents

Diffusion Control in Single-Site Zinc Reticular Amination Catalysts

Zn-containing metal-organic frameworks have been used for the first time as heterogeneous catalysts in the amination of C-Cl bonds. The use of extended bis(pyrazolate) linkers can generate highly porous architectures, which favor the diffusion of amines t

Metal-free, redox-neutral, site-selective access to heteroarylamine via direct radical?radical cross-coupling powered by visible light photocatalysis

Transition-metal-catalyzed C?N bond-forming reactions have emerged as fundamental and powerful tools to construct arylamines, a common structure found in drug agents, natural products, and fine chemicals. Reported herein is an alternative access to heteroarylamine via radical?radical cross-coupling pathway, powered by visible light catalysis without any aid of external oxidant and reductant. Only by visible light irradiation of a photocatalyst, such as a metal-free photocatalyst, does the cascade single-electron transfer event for amines and heteroaryl nitriles occur, demonstrated by steady-state and transient spectroscopic studies, resulting in an amine radical cation and aryl radical anion in situ for C?N bond formation. The metal-free and redox economic nature, high efficiency, and site-selectivity of C?N cross-coupling of a range of available amines, hydroxylamines, and hydrazines with heteroaryl nitriles make this protocol promising in both academic and industrial settings.

Synthesis method of aza-arylamine compound and aza-arylamine compound

The invention provides a synthesis method of an aza-arylamine compound as shown in a formula (I). The synthesis method comprises the following steps: an aza aromatic hydrocarbon compound as shown in aformula (II) reacts with an amine compound as shown in a formula (III) in presence of alkali and under a heating condition, so that u X substituent groups on an A ring of the compound as shown in theformula (II) are substituted by NRR in the compound as shown in the formula (III), and the compound as shown in the formula (I) is obtained, wherein A is an aza six-membered aromatic ring or five-membered aromatic ring, and is an independent single ring or is fused with a ring B; X refers to that the A ring has at least n X substituent groups, each X substituent group is independently selected from the group consisting of F, Cl, Br, I, CN, alkoxy of C and alkylthio of C, and n is a positive integer selected from 1-5; and the alkali is one or a mixture of more selected fromof BuOK, BuONa, BuONa, KHMDS, NaHMDS and LiHMDS. The synthesis method provided by the invention does not need the use of transition metal catalysts, is simple and convenient to operate, is economical and practical and is environmentally friendly. In addition, the invention also provides the aza-arylamine compound prepared by the method.