64910-48-1

Basic information

• Product Name: Benzonitrile, 3-(methylamino)-4-nitro-
• CAS NO: 64910-48-1
• Molecular Formula: C8H7N3O2
• Molecular Weight: 177.162
• Mol File: 64910-48-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 3-(methylamino)-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 3-(methylamino)-4-nitro-(64910-48-1)
• EPA Substance Registry System: Benzonitrile, 3-(methylamino)-4-nitro-(64910-48-1)

Safety Data

• Hazardous Substances Data: 64910-48-1(Hazardous Substances Data)

Upstream product

• 218632-01-0 3-fluoro-4-nitrobenzonitrile 
• 74-89-5 methylamine 
• 34662-29-8 1-chloro-5-cyano-2-nitrobenzene 
• 92241-87-7 3-methoxy-4-nitrobenzamide 
• 67579-92-4 3-methoxy-4-nitrobenzoic acid chloride 
• 5081-36-7 3-methoxy-4-nitrobenzoic acid 
• 177476-75-4 3-methoxy-4-nitrobenzoinitrile 
• 102000-73-7 3-bromo-4-nitrobenzonitrile 
• 593-51-1 methylamine hydrochloride 

Downstream Products

• 360791-73-7 2-(2-hydroxybiphenyl-3-yl)-3-methyl-3H-benzoimidazole-5-carbonitrile 
• 53484-14-3 3-methyl-3H-benzoimidazole-5-carbonitrile 
• 6595-25-1 1.2-Dimethyl-6-benzimidazol-carbonitril 
• 864274-02-2 1-methyl-1H-1,2,3-benzotriazole-6-carbonitrile 
• 181867-19-6 1-methyl-1H-benzo[d]imidazole-6-carbaldehyde 
• 412309-37-6 2-(4-cyano-phenyl)-3-methyl-3H-benzimidazole-5-carbonitrile 
• 64910-49-2 4-amino-3-(methylamino)benzonitrile 

Relevant articles and documents

Cu-Catalyzed C-H Allylation of Benzimidazoles with Allenes

CuH-catalyzed intramolecular cyclization and intermolecular allylation of benzimidazoles with allenes have been described. The reaction proceeded smoothly with the catalytic system of Cu(OAc)2/Xantphos and catalytic amount of (MeO)2MeSiH. This protocol features mild reaction conditions and a good tolerance of substrates bearing electron-withdrawing, electron-donating, or electron-neutral groups. A new catalytic mechanism was proposed for this copper hydride catalytic system.

Synthesis, computational analysis, and antiproliferative activity of novel benzimidazole acrylonitriles as tubulin polymerization inhibitors: Part 2

We used classical linear and microwave-assisted synthesis methods to prepare novel N-substituted, benzimidazole-derived acrylonitriles with antiproliferative activity against several cancer cells in vitro. The most potent systems showed pronounced activit

THIAZOLONES FOR USE AS PI3 KINASE INHIBITORS

Invented is a method of inhibiting the activity/function of PI3 kinases using substituted thiazolones. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, ne