649736-30-1 Usage
General Description
The chemical "2-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[1,2-f][1,2,4]triazin-6-yl)propan-2-ol" is a synthetic compound that belongs to the class of pyrrolo[1,2-f][1,2,4]triazine derivatives. It contains a fluorine-substituted indol structure and a pyrrolo[1,2-f][1,2,4]triazine ring system. This chemical has a propan-2-ol moiety attached to the pyrrolo[1,2-f][1,2,4]triazine ring. It may have potential applications in medicinal chemistry and drug development due to its structural features and potential biological activities. Further research and investigations are necessary to determine its specific properties and potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 649736-30-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,9,7,3 and 6 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 649736-30:
(8*6)+(7*4)+(6*9)+(5*7)+(4*3)+(3*6)+(2*3)+(1*0)=201
201 % 10 = 1
So 649736-30-1 is a valid CAS Registry Number.
649736-30-1Relevant articles and documents
Discovery of brivanib alaninate ((S)-((R)-1-(4-(4-fluoro-2-methyl-1H-indol- 5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan-2-yl) 2-aminopropanoate), a novel prodrug of dual vascular endothelial growth factor receptor-2 and fibroblast growth
Cai, Zhen-Wei,Zhang, Yongzheng,Borzilleri, Robert M.,Qian, Ligang,Barbosa, Stephanie,Wei, Donna,Zheng, Xiaoping,Wu, Lawrence,Fan, Junying,Shi, Zhongping,Wautlet, Barri S.,Mortillo, Steve,Jeyaseelan Sr., Robert,Kukral, Daniel W.,Kamath, Amrita,Marathe, Punit,D'Arienzo, Celia,Derbin, George,Barrish, Joel C.,Robl, Jeffrey A.,Hunt, John T.,Lombardo, Louis J.,Fargnoli, Joseph,Bhide, Rajeev S.
, p. 1976 - 1980 (2008/12/22)
A series of amino acid ester prodrugs of the dual VEGFR-2/FGFR-1 kinase inhibitor 1 (BMS-540215) was prepared in an effort to improve the aqueous solubility and oral bioavailability of the parent compound. These prodrugs were evaluated for their ability t