650628-19-6

Basic information

• Product Name: 1H-Pyrazole-4-carbonitrile, 5-amino-1-(2-methoxyphenyl)-
• CAS NO: 650628-19-6
• Molecular Formula: C11H10N4O
• Molecular Weight: 214.227
• Mol File: 650628-19-6.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazole-4-carbonitrile, 5-amino-1-(2-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-4-carbonitrile, 5-amino-1-(2-methoxyphenyl)-(650628-19-6)
• EPA Substance Registry System: 1H-Pyrazole-4-carbonitrile, 5-amino-1-(2-methoxyphenyl)-(650628-19-6)

Safety Data

• Hazardous Substances Data: 650628-19-6(Hazardous Substances Data)

Usage

Structure

Pyrazole derivative with a carbonitrile group and an amino group attached to a methoxyphenyl group

Potential applications

Pharmaceuticals, agrochemicals

Biological activities

Antimicrobial, antifungal, and antitumor properties

Usage

Building block in the synthesis of various biologically active molecules

Promising results

Potential therapeutic uses in scientific research

Upstream product

• 123-06-8 Ethoxymethylenemalononitrile 
• 18312-46-4 (2-methoxyphenyl)hydrazine 
• 6971-45-5 2-methoxyphenylhydrazine hydrochloride 
• 672-81-1 2-(methoxymethylene)malononitrile 

Downstream Products

• 792953-16-3 (5-amino-1-(2-methoxyphenyl)-1H-pyrazole-4-carboxamide) 
• 791781-10-7 [1-(2-methoxy-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-hydrazine 

Relevant articles and documents

COMBINATION THERAPY FOR TREATING MPS1

The application is directed to compounds of formula (I) and their salts and solvates, wherein B, R1, R2, R3, R3', R4, R4', and R5 are as set forth in the specification, as well as to methods for their preparation, pharmaceutical compositions comprising the same, and use thereof for the treatment and/or prevention of, e.g., MPS1, optionally in combination with α-L-iduronidase or an analog or variant thereof, e.g., laronidase.

AMINO-HETEROCYCLIC COMPOUNDS

The invention provides PDE9-inhibiting compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein R, R1, R2 and R3 are as defined herein. Pharmaceutical compositions containing the compounds of Formul

6-Arylmethyl-substituted pyrazolopyrimidines

The invention relates to novel 6-arylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.