65105-52-4 Usage
Description
Strobilurin B, an enoate ester, is the methyl ester of (2E,3Z,5E)-6-(4-chloro-3-methoxyphenyl)-2-(methoxymethylene)-3-methylhexa-3,5-dienoic acid. It is a compound with significant biological activity, particularly as an antifungal and mitochondrial activity inhibitor.
Uses
Used in Agriculture:
Strobilurin B is used as an antifungal agent for the control of various fungal diseases in crops. It works by inhibiting mitochondrial respiration in fungi, thus preventing their growth and spread.
Used in Pharmaceutical Industry:
Strobilurin B is used as a mitochondrial activity inhibitor of cancer-initiating cells. By targeting and disrupting the mitochondrial function in these cells, Strobilurin B has the potential to be a valuable tool in the development of novel cancer treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 65105-52-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,1,0 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 65105-52:
(7*6)+(6*5)+(5*1)+(4*0)+(3*5)+(2*5)+(1*2)=104
104 % 10 = 4
So 65105-52-4 is a valid CAS Registry Number.
InChI:InChI=1/C17H19ClO4/c1-12(14(11-20-2)17(19)22-4)6-5-7-13-8-9-15(18)16(10-13)21-3/h5-11H,1-4H3/b7-5+,12-6-,14-11+
65105-52-4Relevant articles and documents
The total synthesis of strobilurin B
Popovsky,Stepanov,Grigorieva, N. Ya.
, p. 491 - 496 (2015/02/02)
A new regio- and stereocontrolled total synthesis of the antibiotic strobilurin B is performed in nine steps in 5.5% overall yield.
Total synthesis of strobilurin B using a hetero-bis-metallated pentadiene linchpin
Coleman, Robert S.,Lu, Xiaoling
, p. 423 - 425 (2008/02/05)
An efficient, six-step stereocontrolled total synthesis of the antifungal agent strobilurin B is reported and was based on a convergent bi-directional coupling featuring a hetero-bis-1,4-metallated pentadiene system as the linchpin. The Royal Society of C
